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CompletedNCT02858661Updated Apr 21, 2023

Improving the Diagnosis of Meningitis in Emergency Rooms

An interventional study of Nasopharyngeal swab in Meningitis, sponsored by Assistance Publique Hopitaux De Marseille. Completed at 1 site in France. Per ClinicalTrials.gov, last updated 2023-04-21.

Sponsored by Assistance Publique Hopitaux De Marseille · Not applicable, Interventional, and Diagnostic

From the registry’s dates

  • Registered 3 years 3 months after the study started (first participant enrolled Mar 2013, registered Jul 2016).
Phase
Not applicable
Study type
Interventional
Enrollment
109
Allocation
Not applicable
Sex
All
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Study summary

A point-of-care laboratory (POC) was set at North Hospital, Marseille, France for the diagnosis in less than two hours of meningitis caused by known pathogens, close to the reception of Emergency service. In this instance 30% of patients have no etiological diagnosis after the POC diarrhoea tests . This lab has discovered over 200 new species of bacteria in humans, including vector bacteria and opened the field of large Deoxyribonucleic Acid (DNA ) viruses. Also, the laboratory of emerging viruses discovered many Ribonucleic Acid (RNA) viruses transmitted by arthropods. Based on this collection of new pathogens described in POC laboratory, this study proposes to expand the etiological diagnosis strategy of meningitis after POC test.

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Conditions studied

  • Meningitis

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In context

Meningitis

373 studies on the registry are indexed under Meningitis; 32 are open to participants now.

This study's enrollment of 109 is below the median of 211 across 257 interventional studies indexed under Meningitis.

Browse Meningitis studies →

Lead sponsor

Assistance Publique Hopitaux De Marseille is the lead sponsor of 686 studies on the registry; 148 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patient admitted at hospital for meningitis requiring, for the emergency physician, a microbiological examination with a "POC meningitis kit."
  • Patient who has freely signed the informed written consent
  • Patient affiliated to a social security scheme

Exclusion criteria

Exclusion Criteria:

  • Pregnant woman, parturient or nursing
  • Adult patient under guardianship
  • Patient deprived of liberty under court order
  • Patient refusing or unable to sign the informed consent form.
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Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
109 participants (actual)

Study arms

  • Experimental
    Patients diagnosed with clinical meningitis

    Patients admitted in emergency rooms for clinical meningitis, for which a nasopharyngeal swab will be performed in order to confirm the etiological diagnosis of meningitis

    Other: Nasopharyngeal swab

Interventions

  • OtherNasopharyngeal swab
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What researchers measure

Primary outcomes

  1. Percentage of patients admitted with a meningitis with a confirmed etiological diagnosis

    Time frame: 1 day

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Study locations

1 site
  • Assistance Publique Hopitaux de Marseille
    Marseille, 13354, France
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 21, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02858661
Lead sponsor
Assistance Publique Hopitaux De Marseille
Responsible party
Sponsor
First posted
Aug 8, 2016
Start date
Mar 30, 2013
Primary completion
Feb 8, 2019
Completion
Oct 27, 2022
Last update
Apr 21, 2023

Study contacts

Catherine GEINDRE
study director · Assistance Publique Hôpitaux de Marseille

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.

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