CClinicalTrials.gg
Status unknownNCT02856399Updated Aug 4, 2016

Long-term Effects of Methadone for Cancer Pain

An observational study in Cancer Pain, sponsored by Hospices Civils de Lyon. Status unknown at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-08-04.

Sponsored by Hospices Civils de Lyon · Observational

The sponsor has not verified this record recently (last verified Aug 2016), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
18 Years and older
Sex
All
01

Study summary

The methadone is an useful opioid for the cancer pain treatment, mostly used in second or last line during the opioid rotation. The Methadone had an anti-MNDA effect, and clinicians agree that the methadone could have an effect in neuropathic cancer pain. During a previous study the investigators find that the pain was still improving after the week 2, but they had only a small number of patients still included at this stage and they cannot conclude.

The investigators decide to follow up systematically all the patients undergoing a methadone treatment for cancer pain, at day 28, to study the hypothesis about the long-term pain improvement.

02

Conditions studied

  • Cancer Pain

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Keywords

  • methadone
  • cancer pain
  • long term effect
03

In context

Cancer Pain

338 studies on the registry are indexed under Cancer Pain; 71 are open to participants now.

This study's planned enrollment of 50 is below the median of 140 across 68 observational studies indexed under Cancer Pain.

Browse Cancer Pain studies →

Lead sponsor

Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients undergoing a methadone treatment for cancer pain

Inclusion criteria

  • Patients with t methadone for cancer pain in opioid rotation
  • Able to fill the questionnaire
  • Performance status (PS) from 0 to 2

Exclusion criteria

Exclusion Criteria:

  • Patients PS 3
  • Unable to sign the informed consent
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Difference between EVA pain score at Day 28 and Day 0

    long-term effects of methadone for cancer pain

    Time frame: pain score measure at Day 0 and Day 28

Secondary outcomes

  1. Change in score of neuropathic pain intensity NPSI

    Time frame: Day 0 and Day 28

  2. Change in depression and anxiety score HADS

    Time frame: Day 0 and Day 28

  3. Change in quality of life score QOL C30

    Time frame: Day 0 and Day 28

  4. Side effect record

    Time frame: up to Day 28

07

Study locations

1 of 1 sites recruiting
  • Unité de Soins Palliatifs - Hospices Civils de Lyon - Centre Hospitalier Lyon Sud, 165 Chemin du Grand Revoyet
    Pierre-Bénite, 69310, France
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 4, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02856399
Lead sponsor
Hospices Civils de Lyon
Responsible party
Sponsor
First posted
Aug 4, 2016
Start date
Nov 2014
Primary completion
Aug 2018 (estimated)
Completion
Aug 2018 (estimated)
Last update
Aug 4, 2016

Study contacts

Marilene FILBET, Pr Associate
Contact
marilene.filbet@chu-lyon.fr
(0)478864148 ext. +33
Marilene FILBET, Pr Associate
principal investigator · Hospices Civils de Lyon

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Aug 2016. You cannot join it, but the record below documents what was studied.

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