An interventional study of Observation in Intractable Epilepsy, sponsored by The University of Texas Health Science Center, Houston. Recruiting at 1 site in United States. Open to participants aged 0 Days to 18 Years. Per ClinicalTrials.gov, last updated 2024-12-11.
Sponsored by The University of Texas Health Science Center, Houston · Not applicable, Interventional, and Diagnostic
To determine the utility of diffusion tensor magnetic resonance imaging in the preoperative workup of children with intractable epilepsy referred for surgery.
To determine if diffusion tensor and functional connectivity magnetic resonance imaging helpful to better understand and diagnose intractable epilepsy in children. All enrolled children will undergo standard preoperative and postoperative MRI imaging, plus a 15 minute set of functional connectivity and diffusion tensor sequence with no additional sedation. This imaging data will be stripped of identifiers and be processed to provide both quantitative analysis, resting state functional connectivity changes and three dimensional modeling of white matter tracts adjacent to epileptogenic foci. This study is being done to determine if diffusion tensor and functional connectivity magnetic resonance imaging are helpful to better understand and diagnose intractable epilepsy in children.
1,805 studies on the registry are indexed under Epilepsy; 417 are open to participants now.
This study's planned enrollment of 50 is close to the median of 50 across 1,206 interventional studies indexed under Epilepsy.
Browse Epilepsy studies →The University of Texas Health Science Center, Houston is the lead sponsor of 880 studies on the registry; 209 are open to participants now.
Of its 170 completed or terminated interventional studies of FDA-regulated products, 140 (82%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Observing MRI changes in subjects.
Procedure: Observation
Observation of MRI changes in subjects
Number of participants with seizure outcome as determined by Engel
Time frame: 5 years
Plan to share: No
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The University of Texas Health Science Center, Houston