An observational study in Osteoarthritis, sponsored by The Third Xiangya Hospital of Central South University. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2017-06-12.
Sponsored by The Third Xiangya Hospital of Central South University · Observational
In this study, the investigators use the clinical documentation and imaging data of MRI to do research. Clinical subjects were divided into two groups: osteoarthritis patients and healthy controls without osteoarthritis. Differences of MRI data were studied between two groups.
In this study, the investigators applied high precision MRI technique (with as less as a slice thickness of 0.35 mm and without inter-slice gap), and calculated not only the IPFP maximal sagittal area and IPFP volume, but also the quantitated signal, and compared the differences between healthy controls and osteoarthritis patients. This is an observational cross-sectional study without specific interventions to the subjects. MRI is a regular examination in our hospital. And all subjects are included for the reasons of osteoarthritis (need MRI) and healthy controls (pain but not osteoarthritis, also need MRI). The investigator does not assign specific interventions to the subjects of the study.
4,398 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.
This study's enrollment of 121 is above the median of 100 across 791 observational studies indexed under Osteoarthritis.
Browse Osteoarthritis studies →The Third Xiangya Hospital of Central South University is the lead sponsor of 95 studies on the registry; 49 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Subjects who come to see doctors requiring knee MRI test.
Exclusion Criteria:
3.0 Tesla Magnetic resonance imaging was analyzed. It's the documentation from the outpatients and inpatients with osteoarthritis. It's not the intervention the study applied, but the subjects' disease demands.
Radiation: Magnetic resonance imaging
3.0 Tesla Magnetic resonance imaging was analyzed. It's the documentation from the outpatients and inpatients without osteoarthritis. It's not the intervention the study applied, but the subjects' non-osteoarthritis knee symptom demands.
Radiation: Magnetic resonance imaging
3.0 T Magnetic resonance imaging of knee joints. It does not harm the subjects.
Infrapatellar Fat Pad Volume in MRI
Time frame: collect the data within 24 hours after the subjects did the MRI
| Milestone | Osteoarthritis Patients | Healthy Controls |
|---|---|---|
| Started | 59 | 62 |
| Completed | 59 | 62 |
| Not completed | 0 | 0 |
| mm^3 | Osteoarthritis Patients | Healthy Controls |
|---|---|---|
| Infrapatellar Fat Pad Volume in MRI | 25154.96 ± 4865.37 | 29202.39 ± 7242.63 |
Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Osteoarthritis Patients | — | 0/59 (0%) | 0/59 (0%) |
| Healthy Controls | — | 0/62 (0%) | 0/62 (0%) |
| Age, Continuous(years) | Osteoarthritis Patients | Healthy Controls | Total |
|---|---|---|---|
| Mean | 59.6 ± 9.2 | 38.8 ± 13.6 | 49.9 ± 15.6 |
| Sex: Female, Male(Participants) | Osteoarthritis Patients | Healthy Controls | Total |
|---|---|---|---|
| Female | 36 | 29 | 65 |
| Male | 23 | 33 | 56 |
| BMI(kg/(m^2)) | Osteoarthritis Patients | Healthy Controls | Total |
|---|---|---|---|
| Median | 24.7 ± 3.5 | 22.6 ± 4.4 | 23.6 ± 4.1 |
Plan to share: No
This study is completed, as verified in May 2017. You cannot join it, but the record below documents what was studied.
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The Third Xiangya Hospital of Central South University