An observational study in Obesity and NAFLD, sponsored by Jagiellonian University. Completed. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2019-09-12.
Sponsored by Jagiellonian University · Observational
Up to 300 million people have a BMI over 30kg/m2. Obesity is the cause of many serious diseases, such as type 2 diabetes, hypertension and NAFLD. Bariatric surgery is the only effective method of achieving weight loss in patients with morbid obesity.
The aim of the study is to assess the impact of bariatric surgery on non-alcoholic fatty liver disease in patients operated on due to morbid obesity.
Investigators include 20 patients qualified for the bariatric procedure with BMI > 40 kg/m2 or a BMI > 35kg/m2 with the presence of comorbidities. The average body weight in the group was 143.85kg with an average BMI of 49.16kg/m2. Before the procedure, investigators evaluated the severity of the non-alcoholic fatty liver disease in each patient using the Sherif Saadeh ultrasound scale. Investigators also evaluated the levels of the liver enzymes. Follow up was performed twelve months after surgery.
2,081 studies on the registry are indexed under Liver Diseases; 390 are open to participants now.
This study's enrollment of 20 is below the median of 167 across 681 observational studies indexed under Liver Diseases.
Browse Liver Diseases studies →Jagiellonian University is the lead sponsor of 156 studies on the registry; 34 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The analysis included prospectively collected data from consecutive patients electively operated for morbid obesity in 2015.
Patients at the age of 18-60, meeting the criteria of qualification for the surgical treatment of obesity, i.e. BMI > 40 kg/m2 or BMI > 35 kg/m2 together with accompanying diseases.
Exclusion Criteria:
Patient with morbid obesity defined as a BMI above 40kg/m2 or 35kg/m2 with comorbidities who are qualified for bariatric surgery.
Procedure: Bariatric surgery
Laparoscopic Sleeve Gastrectomy (LSG) Laparoscopic Roux-en-Y Gastric Bypass (LRYGB)
NAFLD
Ultrasound assessment of the severity of NAFLD with the Sherif-Saadeh scale.
Time frame: 12 months
Weight loss after bariatric surgery
Excess Body Mass Index loss (EBMIL)
Time frame: 12 months after surgery
Comorbidities
Number of patients with hypertension and diabetes
Time frame: 12 months after surgery
Liver function impairment
Standard set of blood liver enzymes including aspartate aminotransferase (AST) and alanine aminotransferase (ALT)
Time frame: 12 months after surgery
No study locations are listed for this record.
Plan to share: No — data not entered
This study is completed, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Jagiellonian University