An interventional study of EZ-Blocker in Coronary Artery Bypass, sponsored by Centre Hospitalier Universitaire, Amiens. Terminated at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-12.
Sponsored by Centre Hospitalier Universitaire, Amiens · Not applicable, Interventional, and Prevention
Coronary artery bypass grafting is a current cardiac surgery. Internal thoracic artery is usually taking to restore coronary revascularization, and its dissection can lead to accidental or voluntary pleural effusions. Respiratory complications are frequent, due to the drainage required. In this study, the investigators propose one-lung ventilation to facilitate artery grafting and surgical procedure. The investigators will include all adult patients with elective coronary artery bypass surgery (CABG) by internal thoracic artery, in a prospective, controlled, randomized and monocentric study. The main objective is to demonstrate that one-lung ventilation using EZ-Blocker can reduce pleural effusion defined by presence of drainage and/or pneumothorax on X-ray chest in the ICU.
324 studies on the registry are indexed under Pleural Effusion; 62 are open to participants now.
This study's enrollment of 35 is below the median of 63 across 212 interventional studies indexed under Pleural Effusion.
Browse Pleural Effusion studies →Centre Hospitalier Universitaire, Amiens is the lead sponsor of 576 studies on the registry; 178 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
bi lung ventilation usual practice
one lung ventilation 'EZ-Blocker'
Device: EZ-Blocker
the Blocker group, the EZ-Blocker will be set up after anesthesia induction and standard orotracheal intubation to allow lung exclusion during homolateral internal thoracic artery sampling, and thus a one-lung ventilation. This material will be removed at the end of surgical surgery.
Pleural effusions after coronary artery bypass graft surgery
quantifying the number of thoracic drains (0, 1 or 2), as accidental or voluntary pleural effusion
Time frame: Day 0
absence of pneumothorax
verify the absence of pneumothorax to X-ray chest ( not drained pleural effusion).
Time frame: Day 0
This study is terminated, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Universitaire, Amiens