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CompletedNCT02819427AbsenceUpdated Jun 12, 2026

Concomitant High-resolution Recording of Haemodynamic and Electrical Activities of Children With Typical or Atypical Absence Seizures

An observational study in Epilepsy, sponsored by Centre Hospitalier Universitaire, Amiens. Completed at 1 site in France. Open to participants aged 3 Years to 14 Years. Per ClinicalTrials.gov, last updated 2026-06-12.

Sponsored by Centre Hospitalier Universitaire, Amiens · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
10
Ages
3 Years to 14 Years
Sex
All
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Study summary

This study, conducted in children with typical or atypical "absence" epilepsy, will consist of noninvasive recording of the metabolic activity of the brain concomitantly with electroencephalographic recording during seizures without the need for any additional examination. This examination will be performed by combining near-infrared spectroscopy (NIRS) optical imaging and Electroencephalography (EEG) in a simultaneous High-Resolution (HR) recording.

Surface electroencephalography (EEG) is a valuable tool to assess neuronal dysfunction from a functional point of view and is used in the routine follow-up of epileptic children. Optical imaging is a recent and promising medical imaging technique, which uses near-infrared light. This rapid, noninvasive and harmless quantitative technique can be easily used at the child's bedside or in the ward and provides metabolic information on brain functioning.

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Conditions studied

  • Epilepsy

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Keywords

  • Spectroscopy, Near-Infrared
  • Electroencephalography
  • children
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In context

Epilepsy

1,805 studies on the registry are indexed under Epilepsy; 417 are open to participants now.

This study's enrollment of 10 is below the median of 102 across 521 observational studies indexed under Epilepsy.

Browse Epilepsy studies →

Lead sponsor

Centre Hospitalier Universitaire, Amiens is the lead sponsor of 576 studies on the registry; 178 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
3 Years to 14 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

children with absence epilepsy presenting either typical or atypical seizures

Inclusion criteria

  • Children aged 3 to 14 years
  • Featuring absence epilepsy with typical or atypical seizures characterized by the presence of spontaneous spike-wave flashes with standard EEG

Exclusion criteria

Exclusion Criteria:

  • All children with severe congenital malformation
  • Any refusal of a parent or child
  • Any child with a serious deterioration in the general condition and vital functions
  • Any child with dermatitis of the face or scalp
  • Children under 3 years old or over 14 years
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
10 participants (actual)
Patient registry
No

Groups and cohorts

  • epilepsy

    children with absence epilepsy presenting either typical or atypical seizures

    Device: Near Infra Red Spectroscopy (NIRS) · Device: Electroencephalography (EEG)

Interventions

  • DeviceNear Infra Red Spectroscopy (NIRS)
  • DeviceElectroencephalography (EEG)

    Electroencephalography (EEG) in a simultaneous High-Resolution (HR) recording.

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What researchers measure

Primary outcomes

  1. haemodynamic changes

    haemodynamic changes by optical imaging, during the 4 interictal, preictal, ictal and postictal phases of absence seizures as defined by EEG analysis

    Time frame: Day 0

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Study locations

1 site
  • CHU Amiens
    Amiens, 80054, France
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 12, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02819427
Lead sponsor
Centre Hospitalier Universitaire, Amiens
Responsible party
Sponsor
First posted
Jun 30, 2016
Start date
Apr 3, 2013
Primary completion
Jun 14, 2018
Completion
Jun 14, 2018
Last update
Jun 12, 2026

Study contacts

Fabrice WALLOIS, MD, PhD
principal investigator · CHU Amiens
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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