An observational study in Preterm Neonates, sponsored by Centre Hospitalier Universitaire, Amiens. Completed at 1 site in France. Open to participants aged 0 Days to 7 Days. Per ClinicalTrials.gov, last updated 2026-06-12.
Sponsored by Centre Hospitalier Universitaire, Amiens · Observational
Particular attention is paid to thermal management of preterm neonates in neonatal intensive care units because of the major risk of morbidity associated with hypothermia. Percutaneous central venous catheter placement is essential to ensure adequate caloric intake and intravenous administration of treatments, but this procedure can cause major body temperature variations, responsible for complications in these neonates, as convection incubator function is impaired during opening of the incubator, which can be prolonged (30 minutes to 2 hours) depending on the technical difficulties encountered during catheter placement.
In parallel, the use of a polyethylene bag or sheet in the delivery room and for neonatal transport is now clearly defined and ensures stability or even a considerable temperature gain during transfer immediately after birth. In the light of several clinical cases, the use of a polyethylene bag during central venous catheter placement appears to be effective to prevent body temperature loss in preterm neonates. No data are currently available concerning the value of this method of prevention of hypothermia during this type of procedure.
Preliminary studies conducted by our team on a dummy suggest that a polyethylene bag or sheet could be useful during this procedure by significantly reducing heat loss caused by convection and evaporation. However, compensation phenomena such as generalized vasoconstriction to cold in preterm infants are very poorly described, but can induce a functional conflict between mechanisms ensuring maintenance of homeostasis and those involved in maintenance of blood pressure.
499 studies on the registry are indexed under Hypothermia; 53 are open to participants now.
This study's enrollment of 63 is below the median of 97 across 126 observational studies indexed under Hypothermia.
Browse Hypothermia studies →Centre Hospitalier Universitaire, Amiens is the lead sponsor of 576 studies on the registry; 178 are open to participants now.
Counted across the registry records on this site, refreshed daily.
preterm neonates less than 32 weeks of gestational age (WGA)
Exclusion Criteria:
Device: polyethylene bag
The infant will be wrapped in a polyethylene bag 15 min before starting central venous catheter placement
Temperature
difference between the prehepatic temperature at the beginning of catheter placement and the lowest temperature observed during the procedure
Time frame: 1 hour
This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Universitaire, Amiens