An observational study in Silicosis, sponsored by Chinese University of Hong Kong. Completed at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-07-06.
Sponsored by Chinese University of Hong Kong · Observational
Objectives: This study aims to explore the risk profiles among people with silicosis in Hong Kong underpinned by the Pittsburgh Mind-Body Center model.
Design and subjects: This study will adopt a cross-sectional study design with sampling stratified by participants' degree of incapability. 320 Chinese people diagnosed with silicosis and registered with the Pneumoconiosis Compensation Fund Board will be recruited.
Data collection: A demographic data sheet and the St. George's Respiratory Questionnaire will be used to collect the socio-demographic and clinical characteristics of the participants. The behavioral factors (smoking, drinking, physical activity level, consumption of vegetable and fruits and plasma vitamin C level) as well as the psychological risk factors (anxiety and depressive symptoms, and social support) will be examined by validated questionnaires. Biological and physiological parameters, including insulin resistance, C-reactive protein, hemoglobin, fasting blood glucose and lipid profiles, will be ascertained by fasting blood sample.
Data analysis and expected outcomes: The findings of this study will create the database profile of the physical, psychosocial and disease specific aspects among people with silicosis in Hong Kong, subsequently forming the empirical basis of an intervention to tackle the identified modifiable risks among them.
20 studies on the registry are indexed under Silicosis; 3 are open to participants now.
This study's enrollment of 390 is above the median of 150 across 11 observational studies indexed under Silicosis.
Browse Silicosis studies →Chinese University of Hong Kong is the lead sponsor of 1,454 studies on the registry; 474 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
A convenience sample of 390 eligible participants registered with the Pneumoconiosis Compensation Fund Board will be recruited with stratification by their degree of incapacity [(i) \<30%, (ii) 30% - 60%, and (iii) >60%], in which the minimal number of participants in each strata will be 30.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Other: People with silicosis
Respiratory symptoms and related physical limitation
examined by Hong Kong Chinese version of St. George's Respiratory Questionnaire
Time frame: baseline
Psychological status
Anxiety and depression symptoms measured by the Chinese version of Hospital Anxiety and Depression Scale
Time frame: baseline
Quality of life
examined by the SF-12v2
Time frame: baseline
Social support
measured by the Chinese version of six-item Social Support Questionnaire
Time frame: baseline
Body mass index
BMI in kg/m\^2
Time frame: baseline
waist circumference
WC in cm
Time frame: baseline
12-hour fasting lipid profile
total-cholesterol, HDL-Cholesterol, LDL-cholesterol and triglycerides (in mmol/L)
Time frame: baseline
12-hour fasting glucose
FG in mmol/L
Time frame: baseline
fasting insulin level
insulin in pmol/L
Time frame: baseline
12 hour fasting ascorbic acid level
vit-C in mg/dL
Time frame: baseline
fasting high sensitivity C-reactive protein level
hs-CRP in mg/L
Time frame: baseline
hemoglobin level
hemoglobin in g/dL
Time frame: baseline
smoking and drinking habits, vegetable and fruit intake
questions adopted from the Behavioral Risk Factor Surveillance of the Department of Health, Hong Kong SAR
Time frame: baseline
Physical activity level
measured by the International Physical Activity Questionnaire - Short Form
Time frame: baseline
Plan to share: No
No publications or documents are linked to this record.
Ran from Jun 2016 to primary completion in Apr 2017, 10 months.
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This study is completed, as verified in Jul 2018. You cannot join it, but the record below documents what was studied.
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Chinese University of Hong Kong →