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CompletedNCT02782143Val_mCAM-EDUpdated Sep 13, 2016

Testing the Validity of the "Modified Confusion Assessment Method for the Emergency Department" (mCAM-ED)"

An observational study in Delirium, sponsored by University Hospital, Basel, Switzerland. Completed at 1 site in Switzerland. Open to participants aged 65 Years to 115 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-09-13.

Sponsored by University Hospital, Basel, Switzerland · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
289
Ages
65 Years to 115 Years
Sex
All
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Study summary

The proposed Study validates the accuracy of the modified Confusion Assessment Method for the Emergency Department

Read the detailed description

Delirium is a complex neuropsychiatric syndrome with sudden change in cognition such as disturbance in orientation or memory particularly in elderly patients in the context of acute illness. Multiple complications such as falls or increased duration of hospitalisation may result in delirium. Long-term consequences may result in increased mortality rates and higher admissions rates to nursing homes. In 2012, delirium prevalence in the Emergency Department (ED) of the University Hospital Basel was 9.5% in patients with 65 years and over. Although a systematic delirium management was introduced in 2012, without systematic screening delirium detection rates varies between 20 and 40% only. The risk of non-detection over the complete hospitalisation is high when early delirium detection did not occur in the ED. In a preliminary evaluation we could show the usefulness of the mCAM-ED

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Conditions studied

  • Delirium

Keywords

  • delirium detection
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In context

Delirium

1,057 studies on the registry are indexed under Delirium; 238 are open to participants now.

This study's enrollment of 289 is above the median of 200 across 418 observational studies indexed under Delirium.

Browse Delirium studies →

Lead sponsor

University Hospital, Basel, Switzerland is the lead sponsor of 968 studies on the registry; 191 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
65 Years to 115 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Patients admitted to the emergency department being 65 years and over

Inclusion criteria

  • Age >= 65 years

Exclusion criteria

Exclusion Criteria:

  • patients under resuscitation or fatal illness
  • not speaking German
  • being aphasic
  • being deaf
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
289 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Delirium measured by geriatricians using Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria

    acute confusional states in patients

    Time frame: once during the stay at the emergency department which lasts an average of 24 hours

  2. Delirium measured by geriatricians using DSM-5 criteria

    acute confusional states in patients

    Time frame: once during the stay at the emergency department which lasts an average of 24 hours

  3. Delirium measured by advanced practice nurses using the mCAM-ED

    acute confusional states in patients

    Time frame: once during the stay at the emergency department which lasts an average of 24 hours

  4. degree of concordance between nurses' delirium measurement versus geriatricians' delirium measurement assessed in a four field matrix

    Time frame: once during the stay at the emergency department which lasts an average of 24 hours

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Study locations

1 site
  • University Hospital Basel
    Basel, 4031, Switzerland
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References and documents

Publications

  • Trzepacz, P. T., & Meagher, D. J. (2008). Neuropsychiatric Aspects of Delirium. In S. C. Yudofsky & R. E. Hales (Eds.), Neuropsychiatry and Behavioral Neurosciences (5 ed., pp. 445-518). Washington, DC: American Psychiatric Publishing, Inc.
  • Han JH, Zimmerman EE, Cutler N, Schnelle J, Morandi A, Dittus RS, Storrow AB, Ely EW. Delirium in older emergency department patients: recognition, risk factors, and psychomotor subtypes. Acad Emerg Med. 2009 Mar;16(3):193-200. doi: 10.1111/j.1553-2712.2008.00339.x. Epub 2009 Jan 20. PubMed 19154565 ↗
  • Ryan DJ, O'Regan NA, Caoimh RO, Clare J, O'Connor M, Leonard M, McFarland J, Tighe S, O'Sullivan K, Trzepacz PT, Meagher D, Timmons S. Delirium in an adult acute hospital population: predictors, prevalence and detection. BMJ Open. 2013 Jan 7;3(1):e001772. doi: 10.1136/bmjopen-2012-001772. PubMed 23299110 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 13, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02782143
Lead sponsor
University Hospital, Basel, Switzerland
Responsible party
Sponsor
First posted
May 25, 2016
Start date
Nov 2015
Primary completion
Dec 2015
Completion
Sep 2016
Last update
Sep 13, 2016

Study contacts

Wolfgang Hasemann, PhD
study chair · usb

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.

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