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CompletedNCT02782039SAPL-LUPUSUpdated Nov 20, 2025

Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE)

An observational study in Anti-Phospholipids Syndrome (APS) and Systemic Lupus Erythematosus (SLE), sponsored by Assistance Publique - Hôpitaux de Paris. Completed at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-11-20.

Sponsored by Assistance Publique - Hôpitaux de Paris · Observational

Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
868
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of that register is to collect medical information about patients suffering of APS with or without associated SLE.

Read the detailed description

Recruitment of patients with APS and SLE treated. Retrospective and prospective register.

02

Conditions studied

  • Anti-Phospholipids Syndrome (APS)
  • Systemic Lupus Erythematosus (SLE)
03

In context

Antiphospholipid Syndrome

121 studies on the registry are indexed under Antiphospholipid Syndrome; 51 are open to participants now.

This study's enrollment of 868 is above the median of 181 across 52 observational studies indexed under Antiphospholipid Syndrome.

Browse Antiphospholipid Syndrome studies →

Lead sponsor

Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,505 studies on the registry; 1,006 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients suffering of APS with or without associated SLE

Inclusion criteria

  • Patient with APS
  • Patient with SLE

Exclusion criteria

Exclusion Criteria:

  • Dependent person
  • Hospitalized without consent and not protected by law
  • Detainee
05

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
868 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Number of patients enrolled with Anti-Phospholipids syndrome (APS) and/or Systemic Lupus Erythematosus (SLE)

    Time frame: 5 years

07

Study locations

2 sites
  • Hôpital Cochin
    Paris, PARIS 75014, France
  • Hôpital Claude Huriez
    Lille, 59000, France
08

References and documents

Publications

  • Mariette F, Le Guern V, Nguyen Y, Yelnik C, Morel N, Hachulla E, Lambert M, Guettrot-Imbert G, Mouthon L, Ebbo M, Costedoat-Chalumeau N. Cluster analysis of clinical manifestations assigns systemic lupus erythematosus-phenotype subgroups: A multicentre study on 440 patients. Joint Bone Spine. 2024 Dec;91(6):105760. doi: 10.1016/j.jbspin.2024.105760. Epub 2024 Jul 6. PubMed 38972539 ↗
  • Dupre A, Morel N, Yelnik C, Moguelet P, Le Guern V, Stammler R, Nguyen Y, Paule R, Dufrost V, Ackermann F, Benhamou Y, Godeau B, Lambert M, Duffau P, Mekinian A, Saadoun D, Mouthon L, Hachulla E, Maillard H, Levesque H, Morell-Dubois S, Leroux G, Piette JC, Chasset F, Costedoat-Chalumeau N. Cutaneous Involvement in Catastrophic Antiphospholipid Syndrome in a Multicenter Cohort of 65 Patients. JAMA Dermatol. 2023 Jan 1;159(1):62-67. doi: 10.1001/jamadermatol.2022.5221. PubMed 36477813 ↗
  • Morel N, Bonnet C, Mehawej H, Le Guern V, Perard L, Roumier M, Brezin A, Godeau B, Haroche J, Benhamou Y, Lambert M, Yelnik CM, Maillard N, Bodaghi B, Piette JC, Costedoat-Chalumeau N. CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME AND POSTERIOR OCULAR INVOLVEMENT: Case Series of 11 Patients and Literature Review. Retina. 2021 Nov 1;41(11):2332-2341. doi: 10.1097/IAE.0000000000003185. PubMed 33840791 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 20, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02782039
Lead sponsor
Assistance Publique - Hôpitaux de Paris
Collaborators
URC-CIC Paris Descartes Necker Cochin
Responsible party
Sponsor
First posted
May 25, 2016
Start date
May 17, 2017
Primary completion
Mar 31, 2022
Completion
Mar 31, 2022
Last update
Nov 20, 2025

Study contacts

Nathalie Costedoat-Chalumeau, MD, PhD
principal investigator · Assistance Publique - Hôpitaux de Paris

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2025. You cannot join it, but the record below documents what was studied.

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