An observational study in Spontaneous Bacterial Peritonitis, sponsored by Tanta University. Status unknown at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2017-06-20.
Sponsored by Tanta University · Observational
One of the most common and serious complications in decompensated cirrhotic patients (DCPs) is bacterial infection.The most common infections in DCPs are cases of spontaneous bacterial peritonitis (SBP), which account for 40% 70% of cases, followed by urinary tract infections, pneumonia and cellulitis.
Serum amyloid A (SAA) and C-reactive protein (CRP) are acute-phase proteins predominantly produced and secreted by hepatocytes. Other cells including lymphocytes, monocytes, and macrophages can also produce these proteins. The induction of SAA and CRP synthesis is triggered by a number of cytokines, chiefly IL-6, which is released from a variety of cell types, but mainly from macrophages and monocytes at inflammatory sites
Increased serum CRP and SAA levels have been found in a number of disorders, including bacterial infections, malignancies tissue injuries and tissue rejection. Therefore, new studies of early diagnosis, prevention and treatment are needed to improve clinical outcomes.
185 studies on the registry are indexed under Peritonitis; 25 are open to participants now.
This study's planned enrollment of 100 is below the median of 127 across 59 observational studies indexed under Peritonitis.
Browse Peritonitis studies →Tanta University is the lead sponsor of 963 studies on the registry; 304 are open to participants now.
Of its 16 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Decompensated cirrhosis with SBP Decompensated cirrhosis without SBP
Decompansated cirrhosis with ascites, defined by a combination of any of the following:
Exclusion Criteria:
serum amyloid A level
Other: serum amyloid A level
Serum amyloid A level
Other: serum amyloid A level
serum amyloid A level (SAA)
Number of patients with elevated serum amyloid A
Time frame: 6months
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Jun 2017. You cannot join it, but the record below documents what was studied.
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Tanta University