An interventional study of hyaluronic acid (hyruan) and physical therapy in Adhesive Capsulitis, sponsored by Taipei Veterans General Hospital, Taiwan. Completed at 1 site in Taiwan. Open to participants aged 40 Years to 70 Years. Per ClinicalTrials.gov, last updated 2022-05-17.
Sponsored by Taipei Veterans General Hospital, Taiwan · Not applicable, Interventional, and Treatment
This study was conducted to compare the efficacy of hydrodilatation with hyaluronic acid under ultrasonographic guidance plus physical therapy (PT) with that of PT alone for treating adhesive capsulitis.
Adhesive capsulitis is a common cause of shoulder pain, and the efficacy of most interventions is limited. This study was conducted to compare the efficacy of hydrodilatation with hyaluronic acid under ultrasonographic guidance plus physical therapy (PT) with that of PT alone for treating adhesive capsulitis.
Design: a prospective, single-blinded, randomized, clinical trial
Patient and methods:
Patients with adhesive capsulitis for at least 3 months were enrolled and randomly allocated into group 1 (hydrodilatation with hyaluronic acid under ultrasonographic guidance plus PT) and group 2 (PT alone). The patients were evaluated before treatment and were reevaluated 0, 6, and 12 weeks after the beginning of the treatment. Outcomes measures included a pain scale (visual analog scale), range of motion, Constant shoulder score, Shoulder Pain And Disability Index, and the Short Form-36
411 studies on the registry are indexed under Bursitis; 112 are open to participants now.
This study's enrollment of 62 is above the median of 45 across 371 interventional studies indexed under Bursitis.
Browse Bursitis studies →Taipei Veterans General Hospital, Taiwan is the lead sponsor of 325 studies on the registry; 72 are open to participants now.
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Exclusion Criteria:
patient received ultrasound-guided hydrodilatation with hyaluronic acid plus physical therapy
Drug: hyaluronic acid (hyruan) · Other: physical therapy
patient received physical therapy only
Other: physical therapy
2cc hyaluronic acid
Also known as: hyaluronate
patient received traditional physical therapy, including therapeutic exercise and stretch exercise
Also known as: rehabilitation
change in constant shoulder score
visual analog scale
Time frame: at 6, 12 wk
change in glenohumeral joint range of motion
Shoulder flexion, abduction, external rotation and internal rotation were measured with goniometer with patient in supine position.
Time frame: at 6, 12 wk
change in Short Form-36
The SF-36 consists of eight sections: vitality, physical functioning, bodily pain, general health perceptions, physical role functioning, emotional role functioning, social role functioning and mental health. It consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability.
Time frame: at 6, 12 wk
change in pain intensity
pain intensity was measured by visual analog scale.
Time frame: at 6, 12 wk
change in Shoulder Pain And disability index
The Shoulder Pain and Disability Index (SPADI) is a self-administered questionnaire that consists of two dimensions, one for pain and the other for functional activities. The pain dimension consists of five questions regarding the severity of an individual's pain. Functional activities are assessed with eight questions designed to measure the degree of difficulty an individual has with various activities of daily living that require upper-extremity use. The SPADI takes 5 to 10 minutes for a patient to complete and is the only reliable and valid region-specific measure for the shoulder.
Time frame: at 6, 12 wk
This study is completed, as verified in May 2022. You cannot join it, but the record below documents what was studied.
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Taipei Veterans General Hospital, Taiwan