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CompletedNCT02674074Updated Feb 26, 2016

Evaluation of Corneal Temperature by Infrared Thermography in Glaucoma Patients

An interventional study of infrared thermography in Glaucoma, sponsored by University Hospital, Basel, Switzerland. Completed at 1 site in Switzerland. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-02-26.

Sponsored by University Hospital, Basel, Switzerland · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Not applicable
Ages
18 Years to 65 Years
Sex
All
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Study summary

Measurement of corneal temperature gives indirect information about the ocular blood flow. For this reason corneal temperature can be used as a surrogate to quantify ocular blood flow. It can be measured by means of infrared thermography. This test, however, is not used in an everyday clinical routine so far. In this study is investigated if ocular blood flow disturbances in glaucoma patients can be diagnosed by means of infrared thermography.

Corneal temperature are measured in normal tension glaucoma patients and healthy controls before and after cold provocation test. In the group of patients and the group of controls, subjects with and without a primary vascular dysregulation (PVD) are included. This will allow to analyze and compare the influence of cold provocation on corneal temperature (and indirectly ocular blood flow) in these study Groups.

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Conditions studied

  • Glaucoma

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03

In context

Glaucoma

1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.

This study's enrollment of 40 is below the median of 65 across 1,272 interventional studies indexed under Glaucoma.

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Lead sponsor

University Hospital, Basel, Switzerland is the lead sponsor of 968 studies on the registry; 191 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Inclusion Criteria for Patients:

  • Glaucoma
  • Age 18-65

Exclusion Criteria for patients:

  • No Glaucoma
  • Alcohol consumption
  • Smoking

Inclusion Criteria for Control:

  • No Glaucoma
  • Age 18-65

Exclusion Criteria for control:

  • Alcohol consumption
  • Smoking
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Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    measurement of corneal temperature by infrared thermography

    Device: infrared thermography

Interventions

  • Deviceinfrared thermography

    measurement of corneal temperature by infrared thermography before and after cold provocation

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What researchers measure

Primary outcomes

  1. Corneal temperature measurement by infrared thermography

    measurement of change in corneal temperature starting with first measurement at Baseline and second measurement after 5 minutes

    Time frame: 2 measurements with interval of 5 minutes starting at baseline

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Study locations

1 site
  • Department of Ophthalmology, University Hospital Basel
    Basel, 4055, Switzerland
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 26, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02674074
Lead sponsor
University Hospital, Basel, Switzerland
Responsible party
Sponsor
First posted
Feb 4, 2016
Start date
Jun 2011
Primary completion
Sep 2013
Completion
Sep 2013
Last update
Feb 26, 2016

Study contacts

Josef Flammer, Prof. MD
study chair · University Hospital, Basel, Switzerland

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2016. You cannot join it, but the record below documents what was studied.

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