ClinicalTrials.gg
TerminatedNCT02648763Updated Jan 13, 2025

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

An observational study in Mesothelioma and Solitary Fibrous Tumor of the Pleura, sponsored by Mayo Clinic. Terminated at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-01-13.

Sponsored by Mayo Clinic · Observational

Why this study was terminated
due to low/slow accrual

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Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
33
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-15

Among 188 studies in Mesothelioma with a site in United States — 36 open to participants now, 50 under way, 1 of them phase 3. Mesothelioma · United States.

Enrollment
17th of 23
33 · median 100
Started
2016
with 17 others
Observational
23 of 188
8 open now
Registered
70th of 188
by date
Lead sponsor
5 of 188
Mayo Clinic

Among the 188 studies in Mesothelioma with a site in United States, this one is the 17th largest by enrollment of the 23 observational ones that give a count, is one of 18 that started in 2016, is one of 23 observational ones, and was the 70th registered.

Mesothelioma

305 studies on the registry are indexed under Mesothelioma; 61 are open to participants now.

Browse Mesothelioma studies →

Open to participants now

36 of the 188 studies in Mesothelioma with a site in United States are open now. Recruiting first, the newest first:

31 more — sign in →

All 36 open studies →

A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →

Who these studies take

Of the 48 Mesothelioma studies recruiting now, 33 (69%) set no upper age limit and 4 (8%) stop at 75 or younger; 7 take children under 18; 4 take healthy volunteers.

This study: 18 Years and older · all sexes · no healthy volunteers.

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02

Study summary

The purpose of this study is to evaluate the accuracy of participants imaging versus staging procedures. The investigators will consent subjects that are scheduled to undergo staging procedures to diagnose malignant pleural mesothelioma (including pleuroscopy, bronchoscopy, endobronchial ultrasound and laparoscopy) as part of their standard of care.

03

Conditions studied

  • Mesothelioma
  • Solitary Fibrous Tumor of the Pleura
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients receiving treatment at the Mayo Clinic Rochester that are scheduled to undergo staging procedures to diagnose malignant pleural mesothelioma (including pleuroscopy, bronchoscopy, endobronchial ultrasound and laparoscopy) as part of their standard of care.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Subject provides
  • Subject is >18 years of age
  • Subject is deemed competent for making medical decisions
  • Subject is scheduled to undergo a staging pleuroscopy
  • Subject is a surgical candidate
  • A negative pregnancy test is required in women of , as standard of care.

Exclusion criteria

Exclusion Criteria:

  • Subject is \<18 years old.
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorized to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Childbearing potential

Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).

Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.

05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
33 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Accuracy of surgical staging versus imaging procedures based on surgical findings.

    The staging imaging will be compared with the actual surgical staging procedure to evaluate the accuracy of the imaging.

    Time frame: 2 years

07

Study locations

1 site
  • Mayo Clinic in Rochester
    Rochester, Minnesota 55905, United States
08

References and documents

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jan 2016 to primary completion in Apr 2023, 87 months.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 20, 2015
First posted
Jan 7, 2016
StartActual
Jan 15, 2016
Primary completionActual
Apr 22, 2023
CompletionActual
Apr 22, 2023
Last update
Jan 13, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jan 13, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02648763
Lead sponsor
Mayo Clinic
Responsible party
Dennis Wigle (Principal Investigator, Mayo Clinic) — Principal investigator
First posted
Jan 7, 2016
Start date
Jan 15, 2016
Primary completion
Apr 22, 2023
Completion
Apr 22, 2023
Last update
Jan 13, 2025

Study contacts

Dennis Wigle, MD, PhD
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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