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TerminatedNCT02648763Updated Jan 13, 2025

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

An observational study in Mesothelioma and Solitary Fibrous Tumor of the Pleura, sponsored by Mayo Clinic. Terminated at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-01-13.

Sponsored by Mayo Clinic · Observational

Why this study was terminated
due to low/slow accrual
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
33
Ages
18 Years and older
Sex
All
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Study summary

The purpose of this study is to evaluate the accuracy of participants imaging versus staging procedures. The investigators will consent subjects that are scheduled to undergo staging procedures to diagnose malignant pleural mesothelioma (including pleuroscopy, bronchoscopy, endobronchial ultrasound and laparoscopy) as part of their standard of care.

02

Conditions studied

  • Mesothelioma
  • Solitary Fibrous Tumor of the Pleura
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients receiving treatment at the Mayo Clinic Rochester that are scheduled to undergo staging procedures to diagnose malignant pleural mesothelioma (including pleuroscopy, bronchoscopy, endobronchial ultrasound and laparoscopy) as part of their standard of care.

Inclusion criteria

  • Subject provides informed consent
  • Subject is >18 years of age
  • Subject is deemed competent for making medical decisions
  • Subject is scheduled to undergo a staging pleuroscopy
  • Subject is a surgical candidate
  • A negative pregnancy test is required in women of child-bearing potential, as standard of care.

Exclusion criteria

Exclusion Criteria:

  • Subject is \<18 years old.
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
33 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Accuracy of surgical staging versus imaging procedures based on surgical findings.

    The staging imaging will be compared with the actual surgical staging procedure to evaluate the accuracy of the imaging.

    Time frame: 2 years

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Study locations

1 site
  • Mayo Clinic in Rochester
    Rochester, Minnesota 55905, United States
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References and documents

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Registry details

Key details

Study ID
NCT02648763
Lead sponsor
Mayo Clinic
Responsible party
Dennis Wigle (Principal Investigator, Mayo Clinic) — Principal investigator
First posted
Jan 7, 2016
Start date
Jan 15, 2016
Primary completion
Apr 22, 2023
Completion
Apr 22, 2023
Last update
Jan 13, 2025

Study contacts

Dennis Wigle, MD, PhD
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is terminated, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

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