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CompletedNCT02647567CaffeineUpdated Jan 6, 2016

Caffeine Intake and Additive Effects on Cognition

An interventional study of Caffeine Intake and Placebo Intake in Healthy, sponsored by Universidade Federal do Rio de Janeiro. Completed. Open to male participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-01-06.

Sponsored by Universidade Federal do Rio de Janeiro · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 45 Years
Sex
Male
01

Study summary

Caffeine is a methylxanthine commonly consumed by the population for their psychostimulant properties, and their intake when in moderate doses seem to produce positive effects on stress, mood and memory. So, understanding that a positive effect of aerobic exercise can be displayed also on cognition, as caffeine, when in proper proportions, the investigators do not know if the joining of the two strategies into a single activity would be able to promote additional effects enhancing cognitive processes related to memory, attention, and motor reaction time.

Read the detailed description

Determine if 500 mg of caffeine can generate additional effects to 30 minutes of aerobic exercise enhancing cognitive memory tasks (Rey Auditory Verbal Learning Test - RAVLT), attention (sustained attention span; working speed; Percentual of errors by confusion) and simple reaction time (SRT).

02

Conditions studied

  • Healthy

Keywords

  • Cognitive
  • Aerobic Exercise
  • Performance
03

In context

Lead sponsor

Universidade Federal do Rio de Janeiro is the lead sponsor of 120 studies on the registry; 11 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 45 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • Fighting men
  • Low levels of consumption of caffeine daily

Exclusion criteria

Exclusion Criteria:

  • Use more than 400 mg caffeine day
  • Mental diseases
  • Cognitive deficits
05

Study design

Phase
Not applicable
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Caffeine Intake

    The experimental group ingest 500 mg of caffeine before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

    Other: Caffeine Intake

  • Placebo comparator
    Placebo Intake

    The control group ingest 500 mg of placebo before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

    Other: Placebo Intake

Interventions

  • OtherCaffeine Intake

    The experimental group ingest 500 mg of caffeine before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

    Also known as: Caffeine

  • OtherPlacebo Intake

    The control group ingest 500 mg of placebo before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

    Also known as: Placebo

06

What researchers measure

Primary outcomes

  1. Simple Reaction Time

    Time frame: Acute Change from Baseline Psychomotor test to 1 min after aerobic exercise, and after 30 min

  2. Rey Auditory Verbal Learning Test

    Time frame: Acute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min

  3. Sustained Attention Test

    Time frame: Acute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 6, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02647567
Lead sponsor
Universidade Federal do Rio de Janeiro
Responsible party
Alberto Souza de Sá Filho (Doctorade in Mental Health, Universidade Federal do Rio de Janeiro) — Principal investigator
First posted
Jan 6, 2016
Start date
May 2015
Primary completion
Nov 2015
Completion
Dec 2015
Last update
Jan 6, 2016

Study contacts

Sérgio Machado, PhD
study director · Salgado de Oliveira University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2016. You cannot join it, but the record below documents what was studied.

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