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CompletedNCT02625818GAPUpdated Nov 21, 2024

The Genetic and Affective Prediction Study

An observational study in Mental Disorders, sponsored by St. Olavs Hospital. Completed at 1 site in Norway. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-11-21.

Sponsored by St. Olavs Hospital · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
400
Ages
18 Years and older
Sex
All
01

Study summary

A major proportion of patients admitted to psychiatric acute and emergency departments have symptoms, behaviors or function influenced by implicit or explicit suicidal intention (tendency towards self-harm, or suicide attempt). There is an increased risk of suicide in the acute phase during in-patient stay and after discharge. At present there is no satisfactory tool to predict post-discharge suicide risk.

Multidimensional rating is expected to have better predictive properties than one-dimensional rating for suicidal behavior during in -patient stay and two years after discharge. Multidimensional rating assesses anxiety, panic, agitation, suicidal thoughts and ideations, as well as therapist's reactions during interviews. In the present study the predictive properties of two rating scales for suicidal behavior during in-patient stay and two years after will be compared. One of these is a multidimensional scale: "Multidimensional Assessment of Suicide Risk" (MARIS).

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Conditions studied

  • Mental Disorders

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Keywords

  • Emergency Services, Psychiatric
  • Prognosis
  • Biological markers
  • Anxiety
  • Panic
  • Psychomotor Agitation
  • Self-injurious Behavior
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In context

Mental Disorders

2,107 studies on the registry are indexed under Mental Disorders; 416 are open to participants now.

This study's enrollment of 400 is above the median of 200 across 480 observational studies indexed under Mental Disorders.

Browse Mental Disorders studies →

Lead sponsor

St. Olavs Hospital is the lead sponsor of 165 studies on the registry; 30 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients admitted to the psychiatric acute department for central Norway, St Olavs University Hospital, Trondheim. The department has a catchment area of approximately 240000 inhabitants ≥ 18 years. The hospital has close to 2000 admittances each year

Inclusion criteria

  • acute agitated condition
  • informed consent

Exclusion criteria

Exclusion Criteria:

  • Drug abuse
  • in-patient stay for a fixed time at regular intervals
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
400 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • acute psychiatric condition
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What researchers measure

Primary outcomes

  1. self-inflicted, potentially injurious behavior with intention to die defined as acts needing attendance by physician

    during in-patient stay

    Time frame: 2 weeks

Secondary outcomes

  1. suicide

    Time frame: 2 years after discharge

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Study locations

1 site
  • St Olavs Hospital, Østmarka psychiatric department
    Trondheim, Norway
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 21, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02625818
Lead sponsor
St. Olavs Hospital
Collaborators
Norwegian University of Science and Technology
Responsible party
Sponsor
First posted
Dec 9, 2015
Start date
Jan 2016
Primary completion
Jan 2020
Completion
Jan 2021
Last update
Nov 21, 2024

Study contacts

Randolf Terje Vågen
study director · St Olavs Hospital, Division of Mental Health Care
Nanna Sønnichsen Kayed
study director · Department of Mental Health, Faculty of Medicine and Health, NTNU

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.

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