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CompletedNCT02624427Updated Jun 21, 2017

Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and Corvis ST Tonometer

An interventional study of Measurement of intraocular pressure (IOP) in Glaucoma, sponsored by University of Zurich. Completed. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-06-21.

Sponsored by University of Zurich · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
109
Allocation
Non-randomized
Ages
18 Years and older
Sex
All
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Study summary

The study is investigating Intra ocular pressure (IOP) by Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and the Corvis ST tonometer.

Read the detailed description

The aim of the study is to approach the "true" Intra ocular pressure (IOP) by correlating the difference between IOP by Goldmann Applanation Tonometry to the IOP by Dynamic Contour Tonometry to the biomechanical parameters of the cornea measured by Corvis ST. Therefore the investigators gain new findings about the influence of the biomechanical corneal parameters on the IOP. In order to do so the investigators want to examine 50 Glaucoma eyes and 50 non-Glaucoma Eyes with Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and Corvis ST.

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Conditions studied

  • Glaucoma

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Keywords

  • Glaucoma
  • Intraocular Pressure
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In context

Glaucoma

1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.

This study's enrollment of 109 is above the median of 65 across 1,272 interventional studies indexed under Glaucoma.

Browse Glaucoma studies →

Lead sponsor

University of Zurich is the lead sponsor of 1,030 studies on the registry; 130 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Inclusion Criteria for the glaucoma group:

  • diagnosis of glaucoma
  • 18 years old or older with no upper limit

Exclusion Criteria for the glaucoma group:

  • IOP lowering surgery within the last 3 weeks
  • any corneal surgery in the past
  • bad fixation
  • insufficient measurement quality with any of the study devices

Inclusion Criteria for the healthy control group:

  • no diagnosis of glaucoma
  • 18 years old or older with no upper limit

Exclusion Criteria for the healthy control group:

  • any diagnosis of glaucoma
  • IOP lowering surgery within the last 3 weeks
  • any corneal surgery in the past
  • bad fixation
  • insufficient measurement quality with any of the study devices
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Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
109 participants (actual)

Study arms

  • Experimental
    Glaucoma Eyes

    Measurement of intraocular pressure (IOP)

    Device: Measurement of intraocular pressure (IOP)

  • Active comparator
    Healthy Eyes

    age-matched healthy eyes as controls will undergo Measurement of intraocular pressure (IOP)

    Device: Measurement of intraocular pressure (IOP)

Interventions

  • DeviceMeasurement of intraocular pressure (IOP)

    Measurement of IOP with the following devices: (1) Goldmann tonometer, (2) Dynamic Contour tonometer, and (3) Corvis ST tonometer

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What researchers measure

Primary outcomes

  1. Delta IOP

    IOP difference of Goldmann tonometer and Dynamic Contour tonometer

    Time frame: baseline

Secondary outcomes

  1. Correlation of IOP difference of Goldmann tonometer and Dynamic Contour tonometer with biomechanical corneal properties measured by Corvis ST tonometer

    Corvis ST has an integrated high-speed Scheimpflug camera which records images on which basis the biomechanical corneal parameter are analyzed (corneal thickness in micrometers, corneal applications in millimeters, peak distance in millimeters, radius in millimeters, and deformation amplitude in millimeters). Those biomechanical parameters of the cornea will be correlated to the difference of the IOP measured by GAT and by DCT (GAT - DCT).

    Time frame: baseline

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Study locations

No study locations are listed for this record.

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References and documents

Related links

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 21, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02624427
Lead sponsor
University of Zurich
Responsible party
Sponsor
First posted
Dec 8, 2015
Start date
Dec 2015
Primary completion
Aug 2016
Completion
Nov 2016
Last update
Jun 21, 2017

Study contacts

Jens Funk, MD PhD
principal investigator · UniversityHospital of Zurich, Zurich, Switzerland

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2017. You cannot join it, but the record below documents what was studied.

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