An interventional study of resistance training and aerobic training in Prediabetic State, sponsored by Nanjing University of Traditional Chinese Medicine. Status unknown at 2 sites in China. Open to participants aged 45 Years to 75 Years. Per ClinicalTrials.gov, last updated 2015-09-29.
Sponsored by Nanjing University of Traditional Chinese Medicine · Not applicable, Interventional, and Prevention
This study evaluates the efficacy of a 12-month resistance training on metabolic control and reducing the risk of diabetes.
Most of exercise interventions involved aerobic exercises, investigators were not able to find a single long term study focusing on type 2 diabetes prevention with resistance training and aerobic exercise. It has been known that for those who have already had diabetes, resistance training can reduce insulin resistance and HbA1c level, improve lipid profile, and decrease blood pressure. Based on previous findings, investigators will evaluate how the different exercising interventions impact on insulin resistance, metabolic control, and the incidence and prevalence of diabetes in prediabetes population who receive 12 months of either resistant training or aerobic exercise. Further more, metabolomics approach will be introduced to detect biological markers,and therefore,to analyze the predictive values of metabolomics on long term outcomes of prediabetes population.
999 studies on the registry are indexed under Prediabetic State; 238 are open to participants now.
This study's planned enrollment of 276 is above the median of 65 across 844 interventional studies indexed under Prediabetic State.
Browse Prediabetic State studies →Nanjing University of Traditional Chinese Medicine is the lead sponsor of 16 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Resistance training consisted of 6 different resistance exercises per session using elastic string, and each exercise progressed to 2-3 at maximum resistance lifted 8-10 times.
Behavioral: resistance training
Aerobic training consisted of aerobic exercise and progressed from 15-20min/session at 60% maximum heart rate to 45-50min/session at 75% maximum heart rate.
Behavioral: aerobic training
standard care complied with the daily lifestyle.
Resistance training consisted of 6 different resistance exercises per session using elastic string, and each exercise progressed to 2-3 at maximum resistance lifted 8-10 times.
Aerobic training consisted of aerobic exercise and progressed from 15-20min/session at 60% maximum heart rate to 45-50min/session at 75% maximum heart rate.
glycemic control
Fasting blood glucose, postprandial blood glucose and HbA1c will be measured at 6 months.
Time frame: 6 months
glycemic control
Fasting blood glucose, postprandial blood glucose and HbA1c will be measured at 12 months.
Time frame: 12 months
small molecule metabolites
Biological markers, with the method of metabolomics approach, will be measured at 6 months
Time frame: 6 months
small molecule metabolites
Biological markers, with the method of metabolomics approach, will be measured at 12 months.
Time frame: 12 months
Incidence rate of diabetes
Evaluate the incidence of diabetes in prediabetes population at 6 months.
Time frame: 6 months
Incidence rate of diabetes
Evaluate the incidence of diabetes in prediabetes population at 12 months.
Time frame: 12 months
This study is status unknown, as verified in Sep 2015. You cannot join it, but the record below documents what was studied.
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Nanjing University of Traditional Chinese Medicine