An observational study in Myocardial Infarction and Acute Coronary Syndromes, sponsored by Population Health Research Institute. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-10-25.
Sponsored by Population Health Research Institute · Observational
During primary percutaneous coronary intervention, distal embolization of thrombus and impaired microvascular perfusion has been associated with an increased mortality. Thrombectomy devices during primary percutaneous coronary intervention may prevent distal embolization by reducing thrombus burden and thus improve microvascular perfusion and reduce mortality.
An individual patient meta-analysis of large randomized controlled trials comparing manual thrombectomy versus percutaneous coronary intervention alone in patients with ST elevation myocardial infarction will provide significantly more power to detect differences in mortality as well as important but rare events such as stroke and to assess benefits in pre-defined subgroups.
2,744 studies on the registry are indexed under Myocardial Infarction; 418 are open to participants now.
This study's planned enrollment of 18,000 is above the median of 500 across 983 observational studies indexed under Myocardial Infarction.
Browse Myocardial Infarction studies →Population Health Research Institute is the lead sponsor of 114 studies on the registry; 27 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients with ST elevation myocardial infarction undergoing emergency percutaneous coronary intervention
Exclusion Criteria:
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Subjects from the randomized controlled trials to be included in this meta-analysis will have been randomly allocated to Manual Aspiration Thrombectomy followed by percutaneous coronary intervention (PCI).
Device: Manual Aspiration Thrombectomy
Subjects from the randomized controlled trials to be included in this meta-analysis will have been randomly allocated to percutaneous coronary intervention (PCI) alone without manual aspiration thrombectomy.
Thrombus aspiration
Occurrence of Cardiovascular death
time to event analysis
Time frame: up to 30 days
Occurrence of Cardiovascular death
time to event analysis
Time frame: up to 180 days
Occurrence of Stroke
time to event analysis
Time frame: up to 30 days
No study locations are listed for this record.
Plan to share: Undecided
This study is completed, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
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Population Health Research Institute