An observational study in Myocardial Ischemia, sponsored by Fondazione Toscana Gabriele Monasterio. Status unknown at 1 site in Italy. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-09-16.
Sponsored by Fondazione Toscana Gabriele Monasterio · Observational
The main aim of this study is to compare markers of cardiac injury (Troponin I), inflammatory response and platelets function during minimally invasive mitral valve repair or replacement (MIMV) via right mini-thoracotomy in two standard anaesthetic regimes (sevo \propofol)
The main aim of this study is to compare markers of cardiac injury (Troponin I), inflammatory response and platelets function during minimally invasive mitral valve repair or replacement (MIMV) via right mini-thoracotomy in two standard anaesthetic regimes:
Outlet/residual blood samples coming from routine check will be collected at different time points.
Study will be powered on Troponin I (primary statistical outcome). Original secondary outcome will be considered: platelets activation, left ventricle function, clinical figures (length of stay, inotrops requirements, ventilation times and other relevant).
3,232 studies on the registry are indexed under Myocardial Ischemia; 395 are open to participants now.
This study's planned enrollment of 48 is below the median of 332 across 1,139 observational studies indexed under Myocardial Ischemia.
Browse Myocardial Ischemia studies →Fondazione Toscana Gabriele Monasterio is the lead sponsor of 6 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Age>=18 Pt undergoing elective (or urgent) first-time minimal invasive mitral valve surgery Pt will have to sign informed consent
Exclusion Criteria:
Patients preconditioned with Sevo
Drug: sevofluorane
Patients with no preconditioning
Continuous infusion of sevofluorane
Also known as: SEVO
Myocardial Injury assessed by changes in Troponin values
According to the routine post operative blood testing frame-time troponin sample will collected in the preoperative and postoperative period.
Time frame: properatively-6, 12, 24, 48 and 72 hours after the end of ischaemic cardioplegic arrest
This study is status unknown, as verified in Sep 2015. You cannot join it, but the record below documents what was studied.
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Fondazione Toscana Gabriele Monasterio