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CompletedNCT02469051Updated May 11, 2016

Breath-hold Cardiac Hybrid SPECT/CCTA

An interventional study of Breathhold SPECT-MPI and Standard freebreathing SPECT-MPI in Coronary Artery Disease, sponsored by University of Zurich. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-05-11.

Sponsored by University of Zurich · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

This study aims at combining inspiration breath-hold myocardial perfusion SPECT with coronary CT angiography.

02

Conditions studied

  • Coronary Artery Disease
03

In context

Coronary Artery Disease

5,596 studies on the registry are indexed under Coronary Artery Disease; 955 are open to participants now.

This study's enrollment of 50 is below the median of 123 across 3,435 interventional studies indexed under Coronary Artery Disease.

Browse Coronary Artery Disease studies →

Lead sponsor

University of Zurich is the lead sponsor of 1,030 studies on the registry; 130 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Referral for cardiac hybrid SPECT/CCTA
  • Male and female subjects 18 years of age or older
  • Written informed consent by the participant after information about the project

Exclusion criteria

Exclusion Criteria:

  • Contraindications for coronary CT angiography (including renal failure with a GFR \<30ml/min/1.73m2, allergies to iodinated contrast agents)
  • Pregnancy or breast-feeding
  • Previous coronary revascularisation
  • Inability to follow the examination procedure (e.g. due to language barriers, severe mental disease etc
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
50 participants (actual)

Study arms

  • Other
    Breathhold SPECT-MPI vs. standard freebreathing SPECT-MPI

    Device: Breathhold SPECT-MPI · Device: Standard freebreathing SPECT-MPI · Device: Coronary CT angiography

Interventions

  • DeviceBreathhold SPECT-MPI

    Respiratory triggered SPECT myocardial perfusion imaging

  • DeviceStandard freebreathing SPECT-MPI

    Clinically indicated, standard non-respiratory triggered SPECT myocardial perfusion imaging

  • DeviceCoronary CT angiography

    Clinically indicated coronary CT angiography serving as standard of reference

    Also known as: CCTA

06

What researchers measure

Primary outcomes

  1. Image quality as visually assessed on a Likert scale

    Time frame: 1 day

  2. Number of image artefacts

    Time frame: 1 day

07

Study locations

1 site
  • Department of Nuclear Medicine, University Hospital Zurich
    Zurich, 8091, Switzerland
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 11, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02469051
Lead sponsor
University of Zurich
Responsible party
Sponsor
First posted
Jun 11, 2015
Start date
May 2015
Primary completion
May 2016
Completion
May 2016
Last update
May 11, 2016

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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