An observational study in Severe Brain Injury, sponsored by Nantes University Hospital. Completed at 3 sites in France. Open to participants aged 15 Years to 85 Years. Per ClinicalTrials.gov, last updated 2016-09-13.
Sponsored by Nantes University Hospital · Observational
Severe brain-injured patients require prolonged mechanical ventilation. Weaning these patients from mechanical ventilation is challenging. During neurologic recovery, brain injured patients usually present satisfactory respiratory autonomy. However, the exact timing of extubation is unknown and is frequently delayed because of potential inhalation.
To date, there are no clinical signs available in the current literature that can help the attending physician in the decision-making process of extubation in brain-injured-patients
2,113 studies on the registry are indexed under Brain Injuries; 385 are open to participants now.
This study's enrollment of 450 is above the median of 100 across 690 observational studies indexed under Brain Injuries.
Browse Brain Injuries studies →Nantes University Hospital is the lead sponsor of 825 studies on the registry; 195 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients hospitalized in ICU for severe brain injury
Exclusion Criteria:
Patients with brain-injury
Other: Collection of medical data from ICU patients
A code will be applied to each patient included. Medical data such as demography, ISS, clinical exam at time of extubation, extubation failure, tracheotomy, will be collected during ICU stay.
Extubation failure
Extubation failure is regarded as the need of intubation in the 48 hours following extubation Establish clinial signs before extubation that can predict extubation failure Realization of a systematic clinical examination by the attending physician before performing extubation in severe brain-injured patients
Time frame: In the 48 hours following extubation
Impact of extubation failure
Impact of extubation failure on * Duration of mechanical ventilation * Length of ICU stay * Mortality Describing reasons
Time frame: Median 14 days after Intensive Care Unit (ICU) admission
This study is completed, as verified in Apr 2015. You cannot join it, but the record below documents what was studied.
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Nantes University Hospital