An interventional study of Heating and cooling combination therapy and Sham heating and cooling therapy in Chronic Low Back Pain, sponsored by Eun Jung Kim. Status unknown at 1 site in Korea, Republic of. Open to participants aged 20 Years to 75 Years. Per ClinicalTrials.gov, last updated 2014-11-13.
Sponsored by Eun Jung Kim · Not applicable, Interventional, and Treatment
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Among 60 studies in Low Back Pain with a site in Korea, Republic of — 9 open to participants now, 11 under way, none of them phase 3. Low Back Pain · Korea, Republic of.
Among the 60 studies in Low Back Pain with a site in Korea, Republic of, this one is the 21st largest by planned enrollment of the 47 interventional ones that give a count, is one of 5 that started in 2014, is one of 27 with no phase, and was the 20th registered.
2,923 studies on the registry are indexed under Low Back Pain; 579 are open to participants now.
Browse Low Back Pain studies →9 of the 60 studies in Low Back Pain with a site in Korea, Republic of are open now. Recruiting first, the newest first:
Keimyung University Dongsan Medical Center · Sites in Korea, Republic of
Ages 20–80
Keimyung University Dongsan Medical Center · Sites in Korea, Republic of
Ages 20–80
Keimyung University Dongsan Medical Center · Sites in Korea, Republic of
Ages 20–80
Jaseng Medical Foundation · Sites in Korea, Republic of
Ages 19–69
Jae Yong Jeon, MD · Sites in Korea, Republic of
Ages 30–65 · Healthy volunteers
A study can be open while its sites in Korea, Republic of have not opened yet or have stopped. Only those recruiting at a site in Korea, Republic of →
Of the 332 Low Back Pain studies recruiting now, 92 (28%) set no upper age limit and 210 (63%) stop at 75 or younger; 8 take children under 18; 46 take healthy volunteers.
This study: 20 Years to 75 Years · all sexes · no healthy volunteers.
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60 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 3 · Phase 2 6 · Phase 3 9 · Phase 4 4
First in 2005; this study’s year is marked. 5 started in 2014.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 80 is above the median of 60 across 2,364 interventional studies indexed under Low Back Pain.
Median enrollment 70 across the 47 interventional studies, 104 across the 12 observational. Of the 37 that completed or were terminated, 3 (8%) have results posted.
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12 of 60 have an industry lead sponsor. The 10 most frequent:
Eun Jung Kim is the lead sponsor of 5 studies on the registry; none are open to participants now.
Eun Jung Kim has 1 study filed under Low Back Pain — fewer than ten, so there is no comparison to draw.
3 of the studies in Low Back Pain with a site in Korea, Republic of that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07058376Jaseng Medical FoundationClinical Research of Effectiveness and Safety of Herbal Medicine Strategy for Chronic Low Back Pain | 2026-12-31 |
| NCT07807839Keimyung University Dongsan Medical CenterStudy of Correlation Between Serum BDNF Levels and Pfirmann Grading and IL- 1β | 2027-08-30 |
| NCT07776366Keimyung University Dongsan Medical CenterStudy of Correlation Between the Level of Intradiscal Periostin Expression and Pfirrmann Grading | 2027-08-30 |
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Among the 60 studies in Low Back Pain with a site in Korea, Republic of, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
The purpose of this study is to verify the efficacy and safety of heating and cooling combination therapeutic device (OCH-S100) for patients with chronic low back pain (LBP).
The investigators targeted the patients with chronic LBP. After treatment in 2 groups - real heating and cooling combination treatment and sham heating and cooling combination treatment - the investigators will compare the effects of pain relief and improvement in disability and range of motion of lumbar region. So the investigators will confirm the efficacy of heating and cooling combination therapy, and further the best treatment method. In addition, the investigators are going to evaluate the safety of abnormal reaction during the treatment.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The patients in this group received heating and cooling combination therapy by a certified Korean Medicine Doctor with more than 6 years of oriental medicine college education and 2 years of clinical experience. Doctor press 8 acupuncture points which is treated in LBP patients and select the most painful 2 acupuncture points. Device's probe is attached to the acupuncture points in 15 minutes. Probe's temperature is changed 5 cycles from maximum 45℃ to minimum 15℃.
Device: Heating and cooling combination therapy
The patients in this group received sham heating and cooling combination therapy in same conditions of treatment group except the temperature. Before the treatment begin, caregiver measure the patient's skin temperature. Then probe's temperature is changed 5 cycles from 1℃ over the skin temperature to 1℃ under the skin temperature.
Device: Sham heating and cooling therapy
The treatment was applied 10 times for 4 weeks. Most painful 2 points in 8 acupuncture points(both side of Bladder meridian23 (BL23), BL24, BL25, BL26) were used for all the patients assigned to this group.
Also known as: OCH-S100
The treatment was applied 10 times for 4 weeks. The sham heating and cooling combination therapy was applied on the 2 of 8 same acupuncture points as in the treatment group.
Also known as: OCH-S100
Change from baseline in 100mm Pain Visual Analogue Scale (VAS)
The patient is asked to indicate their perceived pain intensity along a 100 mm horizontal line, where '0' represents 'no pain' and '100', 'unbearable pain'
Time frame: at baseline and 4 4 weeks later from baseline
Change from baseline in 100mm Pain Visual Analogue Scale (VAS)
The patient is asked to indicate their perceived pain intensity along a 100 mm horizontal line, where '0' represents 'no pain' and '100', 'unbearable pain'
Time frame: estimately every 2.8 days from baseline to 4 weeks later, and 4 weeks later from the end of treatment
Change from baseline in Korean Oswestry disability index (KODI)
KODI is checked by the patients. KODI is a questionnaire to measure the back-related disability. KODI consists of combination of physical and social restriction through 9 questions covering different dimensions of daily living.
Time frame: at baseline, 2 weeks and 4 weeks later from baseline, and 4 weeks later from the end of treatment
Change from baseline in Korean Roland Morris Disability Questionnaire (KRMDQ)
KRMDQ is checked by the patients. KRMDQ is a questionnaire to measure the back-related disability. KRMDQ consists of 24 questions answered yes or no.
Time frame: at baseline, 2 weeks and 4 weeks later from baseline, and 4 weeks later from the end of treatment
Change from baseline in Traditional Medicine Back pain Questionnaire (TMBQ)
TMBQ is checked by the patients. TMBQ is a questionnaire to measure the back-related disability in aspect of oriental medicine.
Time frame: at baseline, 2 weeks and 4 weeks later from baseline, and 4 weeks later from the end of treatment
Change from baseline in Modified schöber test
Modified schöber test measures the flexion range of motion of lumbar spine. First, investigator marks the point at patients' lumbosacral junction. Then also marks the points at upper 10cm and lower 5cm of the former point in standing position. After marking the 3 points, patients bend anteriorly as best he or she can. Then, investigator measures the length of the latter 2 points.
Time frame: at baseline, 2 weeks and 4 weeks later from baseline, and 4 weeks later from the end of treatment
Change from baseline in Finger-to-floor distance
Finger-to-floor distance measures the flexion range of motion of lumbar spine. Patients stand on the box which height is 20cm. Then, patients bend anteriorly in extension of knee and upper limb. Investigator measures the length from floor to 3rd finger.
Time frame: at baseline, 2 weeks and 4 weeks later from baseline, and 4 weeks later from the end of treatment
Change from baseline in Finger-to-thigh distraction
Finger-to-thigh distraction measures the lateral bending range of motion of lumbar spine. Patients stand on the box which height is 20cm. Then, patients bend laterally in extension of knee and upper limb. Investigator measures the length from floor to 3rd finger.
Time frame: at baseline, 2 weeks and 4 weeks later from baseline, and 4 weeks later from the end of treatment
Adverse Events
Any unpredicted symptoms were checked at each follow up visit and if any, the symptom, time of occurrence, and length of duration were recorded and reported.
Time frame: estimately every 2.8 days from baseline to 4 weeks later, and 4 weeks later from the end of treatment
The record gives a start of Sep 2014, a primary completion of Sep 2015 and a completion of Sep 2015. It does not say whether these dates are actual or estimated.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Nov 2014. You cannot join it, but the record below documents what was studied.
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Eun Jung Kim