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CompletedNCT02284789CAJASUpdated Dec 3, 2015

Colorado Adult Joint Assessment Scale (CAJAS) Validation

An interventional study of Colorado Adult Joint Assessment Evaluation in Hemophilia A, sponsored by Bayer. Completed at 4 sites in United States. Open to male participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2015-12-03.

Sponsored by Bayer · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
18 Years to 50 Years
Sex
Male
01

Study summary

To obtain evidence of content validity and reliability of the Colorado Adult Joint Assessment Scale (CAJAS), a clinician-reported outcome (ClinRO) measure, as adapted for use in a population of adults with moderate to severe hemophilia A treated with coagulation factor VIII (FVIII) therapy as secondary prophylaxis or episodic treatment.

02

Conditions studied

  • Hemophilia A

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Keywords

  • Hemophilia
03

In context

Hemophilia A

866 studies on the registry are indexed under Hemophilia A; 137 are open to participants now.

This study's enrollment of 30 is close to the median of 28 across 512 interventional studies indexed under Hemophilia A.

Browse Hemophilia A studies →

Lead sponsor

Bayer is the lead sponsor of 1,643 studies on the registry; 57 are open to participants now.

Of its 209 completed or terminated interventional studies of FDA-regulated products, 129 (62%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
Male
Accepts healthy volunteers
No

Inclusion criteria

  • Male, 18 to 50 years of age
  • Diagnosis of moderate to severe hemophilia A (documented \<1-2% Factor VIII Concentration [FVIII:C])
  • Willing to maintain current FVIII treatment regimen, whether prophylactic or on-demand, for the duration of the study

Exclusion criteria

Exclusion Criteria:

  • Routine need for wheelchair or routine need for two canes or crutches
  • Diagnosis of another bleeding disorder such as von Willebrand Disease
  • Known event that would interfere with the scheduled CAJAS evaluations (e.g., elective joint surgery, vacation)
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Study design

Phase
Not applicable
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Other
    CAJAS evaluation

    Other: Colorado Adult Joint Assessment Evaluation

Interventions

  • OtherColorado Adult Joint Assessment Evaluation

    Physical evaluation of 6 joints, ankles, knees and elbows

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What researchers measure

Primary outcomes

  1. Colorado Adult Joint Assessment Score (CAJAS)

    Time frame: Up to 25 days

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Study locations

4 sites
  • Orange, California 92868, United States
  • Aurora, Colorado 80045, United States
  • Indianapolis, Indiana 46260, United States
  • Portland, Oregon 97239, United States
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 3, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02284789
Lead sponsor
Bayer
Responsible party
Sponsor
First posted
Nov 6, 2014
Start date
Feb 2015
Primary completion
Oct 2015
Completion
Oct 2015
Last update
Dec 3, 2015

Study contacts

Bayer Study Director
study director · Bayer

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2015. You cannot join it, but the record below documents what was studied.

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