An interventional study of Spinal injection bupivacaine/morphine and subcutaneum injection lidocaine in Spinal Bupivacaine/Morphine in Laparoscopic Surgery, sponsored by Maasstad Hospital. Completed at 1 site in Netherlands. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-08-08.
Sponsored by Maasstad Hospital · Not applicable, Interventional, and Treatment
The objective of this study is to determine if a single spinal shot of morphine can decrease post-operative opioid-use, and thereby decrease opioid side-effects and lead to a quicker recovery after surgery.
We expect that in laparoscopic gastro-intestinal surgery, a single shot spinal with bupicavaine/morphine will result in a better analgesia in hte first 48 hours. Herby the patients will require less systemic opioids, which will decrease the side-effects. Furthermore, we expect the patients to recover quicker and show an earlier mobilisation and a shorter hospital stay.
The objective of this study is to determine if a single spinal shot of morphine can decrease post-operative opioid-use, and thereby decrease opioid side-effects and lead to a quicker recovery after surgery.
Maasstad Hospital is the lead sponsor of 21 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients receive spinal injection Bupivacaine/Morphine
Drug: Spinal injection bupivacaine/morphine
Placebo subcutaneum injections
Drug: subcutaneum injection lidocaine
Spinal injection bupivacaine/morphine in laparoscopic surgery
Also known as: injection
placebo injection
Also known as: placebo
Duration of hospital stay
Time frame: first 48 hours
use of piritramide by PCIA-pump in mg
Time frame: 48 hours
patient-satisfactory on a 4-point scale
Time frame: 120 hours/ 5 days
the occurence of side-effects (nausea, pruritus, drowsiness)
Time frame: 120 hours/ 5 days
time to mobilisation
Time frame: 120 hours/ 5 days
time to bowel movement
Time frame: 120 hours/ 5 days
abdominal compliance during laparoscopy in L/mmHg
Time frame: The compliance will be measured for the duration of the surgery, an expected average of 2 hours.
Difficulty of surgery
Time frame: The difficulty of surgery will be measured for the duration of the surgery, an expected average of 2 hours
This study is completed, as verified in Dec 2016. You cannot join it, but the record below documents what was studied.
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Maasstad Hospital