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CompletedNCT02170454rTMSvideoSSUpdated Jun 23, 2014

Effect of Pharyngeal Inhibition by rTMS on Swallowing Function

An interventional study of magnetic stimulation in Oropharyngeal Dysphagia, sponsored by University Hospital, Rouen. Completed at 1 site in France. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-06-23.

Sponsored by University Hospital, Rouen · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
10
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
All
01

Study summary

The aim of this study is to test the hypothesis that rTMS on the dominant swallowing hemisphere is able to modify swallowing coordination.

Read the detailed description

The aim of the study is to demonstrate that rTMS (on the dominant hemisphere, on the nondominant hemisphere and placebo rTMS) are able to modify swallowing coordination on healthy subjects. Swallowing function will be studied before and after rTMS with videomanometry.

02

Conditions studied

  • Oropharyngeal Dysphagia

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Keywords

  • neuromodulation
  • swallowing
  • magnetic stimulation
  • healthy subjects
03

In context

Deglutition Disorders

710 studies on the registry are indexed under Deglutition Disorders; 219 are open to participants now.

This study's enrollment of 10 is below the median of 60 across 471 interventional studies indexed under Deglutition Disorders.

Browse Deglutition Disorders studies →

Lead sponsor

University Hospital, Rouen is the lead sponsor of 410 studies on the registry; 104 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • 18-50 years old
  • healthy subjects

Exclusion criteria

Exclusion Criteria:

  • epilepsia
  • brain injury
  • stroke
  • pregnancy
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Single group
Masking
Single (Participant)
Enrollment
10 participants (actual)

Study arms

  • Active comparator
    rTMS

    rTMS on pharyngeal cortical area in healthy subjects

    Procedure: magnetic stimulation

  • Placebo comparator
    Placebo

    Sham rTMS on pharyngeal cortical area in healthy subjects

    Procedure: magnetic stimulation

Interventions

  • Proceduremagnetic stimulation

    rTMS on pharyngeal cortical area in healthy subjects or sham rTMS on pharyngeal cortical area in healthy subjects

06

What researchers measure

Primary outcomes

  1. pharyngeal pressure

    Swallowing function will be studied before and after rTMS with videomanometry

    Time frame: Day 1

Secondary outcomes

  1. swallowing time

    Swallowing function will be studied before and after rTMS with videomanometry

    Time frame: Day 1

07

Study locations

1 site
  • VERIN
    Rouen, 76031, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 23, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02170454
Lead sponsor
University Hospital, Rouen
Responsible party
Sponsor
First posted
Jun 23, 2014
Start date
Jun 2008
Primary completion
Nov 2008
Completion
Jun 2009
Last update
Jun 23, 2014

Study contacts

Eric VERIN, MDPhD
principal investigator · Rouen University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2014. You cannot join it, but the record below documents what was studied.

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