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CompletedNCT02154165Updated Jun 3, 2014

Comparison Between Turquoise and Blue Light in Treatment of Neonatal Jaundice Using Light Emission Diodes

An interventional study of Phototherapy in Uncomplicated Neonatal Hyperbilirubinemia, sponsored by University of Aarhus. Completed at 1 site in Denmark. Open to participants aged 33 Weeks and older. Per ClinicalTrials.gov, last updated 2014-06-03.

Sponsored by University of Aarhus · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
33 Weeks and older
Sex
All
01

Study summary

The optimal wavelength for phototherapy for neonatal jaundice remains to be clarified by clinical studies. Previous iv vivo studies have shown that turquoise light at wavelength about 490 nm is more efficacious than blue light at wavelength 460 nm, which is the golden standard in phototherapy treatment today. Though, previous studies used light tubes, today we use light emitting diodes (LED'S).

The overall aim of this study was therefore to compare the efficacy of turquoise LED's versus blue LED's for decreasing total serum bilirubin in neonates with gestational age > 33 weeks and uncomplicated hyperbilirubinemia.

02

Conditions studied

  • Uncomplicated Neonatal Hyperbilirubinemia

Keywords

  • Neonatal hyperbilirubinemia
  • Phototherapy
  • Light emitting diodes
  • Blue light
  • Turquoise light
03

In context

Jaundice, Neonatal

105 studies on the registry are indexed under Jaundice, Neonatal; 27 are open to participants now.

This study's enrollment of 90 is below the median of 134 across 74 interventional studies indexed under Jaundice, Neonatal.

Browse Jaundice, Neonatal studies →

Lead sponsor

University of Aarhus is the lead sponsor of 1,274 studies on the registry; 183 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
33 Weeks and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Newborns with gestational age >33 weeks and neonatal hyperbilirubinemia requiring treatment with phototherapy according to the national guidelines

Exclusion criteria

Exclusion Criteria:

  • Haemolytic disease (Rhesus and Kell blood type isoimmunization, spherocytosis)
  • Liver disease
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
90 participants (actual)

Study arms

  • Active comparator
    Blue light wavelenght 460 nm

    Other: Phototherapy

  • Active comparator
    Turquoise light wavelength 499 nm

    Other: Phototherapy

Interventions

  • OtherPhototherapy

    The infants were randomized to phototherapy with either blue og turquoise light

06

What researchers measure

Primary outcomes

  1. Decrease in total serum bilirubin

    The infants were treated with phototherapy for 24 hours, which is the standard treatment.

    Time frame: 24 hours

07

Study locations

1 site
  • Neonatal department, Aalborg University Hospital
    Aalborg, 9000, Denmark
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 3, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02154165
Lead sponsor
University of Aarhus
Responsible party
Helene Nørrelund (MD, University of Aarhus) — Principal investigator
First posted
Jun 3, 2014
Start date
Jan 2013
Primary completion
Dec 2013
Completion
Dec 2013
Last update
Jun 3, 2014

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in May 2014. You cannot join it, but the record below documents what was studied.

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