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Status unknownNCT02113748Updated Apr 15, 2014

Downhill Walking Training in COPD

An interventional study of Downhill walking training and Conventional walking training in Pulmonary Disease, Chronic Obstructive, sponsored by KU Leuven. Status unknown at 1 site in Belgium. Per ClinicalTrials.gov, last updated 2014-04-15.

Sponsored by KU Leuven · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Apr 2014), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
42
Allocation
Randomized
Sex
All
01

Study summary

This randomized control trial will investigate whether a modality that generates more contractile muscle fatigue with lower ventilatory requirements render better results after a 12-week exercise training program in subjects with COPD.

Subjects will be randomized to either exercise in a training program including downhill walking or to exercise in a training program including conventional walking.

02

Conditions studied

  • Pulmonary Disease, Chronic Obstructive

Keywords

  • Pulmonary disease, chronic obstructive
  • Downhill walking
  • exercise
03

In context

Lung Diseases

3,303 studies on the registry are indexed under Lung Diseases; 355 are open to participants now.

This study's planned enrollment of 42 is below the median of 72 across 2,118 interventional studies indexed under Lung Diseases.

Browse Lung Diseases studies →

Lead sponsor

KU Leuven is the lead sponsor of 358 studies on the registry; 62 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients with a primary diagnosis of COPD according to internationally accepted guidelines
  • Patients referred to the outpatient PR program of Gasthuisberg University Hospital(Leuven, Belgium)

Exclusion criteria

Exclusion Criteria:

  • Any underlying disease or musculoskeletal limitation that could impair the ability to perform any of the exercise training modalities
  • Absence of exacerbations in the previous month before entering the present study
  • Patients included on the waiting list for lung transplantation
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
42 participants (estimated)

Study arms

  • Experimental
    Downhill walking training

    Exercise training including treadmill walking with a negative inclination.

    Other: Downhill walking training

  • Active comparator
    Conventional walking training

    Exercise training including treadmill walking without inclination. Possible to progress training intensity with positive inclinations.

    Other: Conventional walking training

Interventions

  • OtherDownhill walking training

    Walk on a treadmill with a negative inclination.

  • OtherConventional walking training

    Walk on a treadmill without inclination. Possible to progress training intensity with positive inclinations

06

What researchers measure

Primary outcomes

  1. changes in 6-minute walking distance

    Time frame: changes from baseline to Week 12

07

Study locations

1 of 1 sites recruiting
  • University Hospitals Leuven
    Leuven, Vl-Brabant 3000, Belgium
    • Thierry Troosters, PhD · Contact · Thierry.Troosters@kuleuven.be
    • Carlos Augusto Camillo, MSc · Sub investigator
    • Thierry Troosters, PhD · Principal investigator
    • Wim Janssens, MD, PhD · Principal investigator
    Recruiting
08

References and documents

Publications

  • Camillo CA, Osadnik CR, Burtin C, Everaerts S, Hornikx M, Demeyer H, Loeckx M, Rodrigues FM, Maes K, Gayan-Ramirez G, Janssens W, Troosters T. Effects of downhill walking in pulmonary rehabilitation for patients with COPD: a randomised controlled trial. Eur Respir J. 2020 Sep 17;56(3):2000639. doi: 10.1183/13993003.00639-2020. Print 2020 Sep. PubMed 32444407 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 15, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02113748
Lead sponsor
KU Leuven
Collaborators
Research Foundation Flanders, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Responsible party
Thierry Troosters (Prof., KU Leuven) — Principal investigator
First posted
Apr 15, 2014
Start date
Apr 2014
Primary completion
Apr 2015 (estimated)
Last update
Apr 15, 2014

Study contacts

Thierry Troosters, PhD
Contact
Thierry.Troosters@kuleuven.be
Thierry Troosters, PhD
principal investigator · KU Leuven

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Apr 2014. You cannot join it, but the record below documents what was studied.

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