CClinicalTrials.gg
CompletedNCT02110511BFEUpdated Apr 10, 2014

Body Responses to Bean Physical Form and "Beano"

An interventional study of blended lentils and whole lentils in Appetite and Glucose Responses, sponsored by Purdue University. Completed at 1 site in United States. Open to participants aged 18 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-04-10.

Sponsored by Purdue University · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
14
Allocation
Randomized
Ages
18 Years to 55 Years
Sex
All
01

Study summary

The aim of this study is to determine the effects of bean physical form (whole versus blended) and Beano on postprandial responses. The postprandial responses the investigators will examine include blood glucose, appetite, metabolic rate, physical symptoms, and mood. To accomplish this aim the investigators will conduct a randomized, placebo-controlled trial in overweight and obese but otherwise healthy (non-diabetic) men and women

02

Conditions studied

  • Appetite and Glucose Responses
03

In context

Lead sponsor

Purdue University is the lead sponsor of 168 studies on the registry; 23 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Aged 18-55 years old
  • Body mass index (BMI) 18.5-40 kg/m2
  • Generally healthy
  • A non-smoker
  • Any ethnicity
  • Free of chronic diseases and not taking medications or dietary supplements known to affect energy regulation or appetite

Exclusion criteria

Exclusion Criteria:

  • Beano drug label warnings including galactosemia, severe liver or kidney disease, allergies or sensitivities to any of the ingredients in Beano
  • Peri and postmenopausal women
  • Pregnant or lactating women (currently and within the past 1 year)
  • Currently dieting or consuming unusual or a medically prescribed diet
  • Net weight loss or gain (>5 lbs) within the last six months
  • Consuming 1/2c per day or more of legumes, not including peanuts
  • Having taken Beano any time in the past 3 months
  • Extreme problems digesting beans
  • Fasting glucose >126 mg/dl
  • Blood pressure >140/90 mmHg
  • Moderate intensity or higher intensity exercise > 6 h/wk
  • Predicted energy requirement \< 2000 kcal/d or >4000 kcal/d
05

Study design

Phase
Not applicable
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Double (Participant, Investigator)
Enrollment
14 participants (actual)

Study arms

  • Experimental
    alpha-gal & blended lentils

    3 capsules of alpha-gal taken with blended lentils

    Other: blended lentils

  • Experimental
    alpha-gal & whole lentils

    3 calpsules of alpha-gal taken with whole lentils

    Other: whole lentils

  • Experimental
    alpha-gal & no lentils

    3 capsules of alpha-gal taken with no lentils control

    Other: no lentils

  • Placebo comparator
    Placebo & blended lentils

    3 capsules of placebo taken with blended lentils

    Other: blended lentils

  • Placebo comparator
    Placebo & whole lentils

    3 capsules of placebo taken with whole lentils

    Other: whole lentils

  • Placebo comparator
    Placebo & no lentils

    3 capsules of placebo taken with no lentils control

    Other: no lentils

Interventions

  • Otherblended lentils

    blended lentils burritto breakfast

  • Otherwhole lentils

    whole lentils breakfast burritto

  • Otherno lentils

    No lentils control breakfast burritto

06

What researchers measure

Primary outcomes

  1. Appetite

    Subjects were given an appetite questionnaire to complete at time 0, 20, 40, 60, 120 and 180

    Time frame: 3 hours

Secondary outcomes

  1. Blood glucose

    Finger prick blood were taken at time 0, 20, 40, 60, 120 and 180 for glucose measurement using a glucometer

    Time frame: 3 hours

  2. fasting and postprandial energy expentidure

    Fasting energy expenditure was measured for thirty minutes before meal and beano intervensions were given and at postprandial time points 20, 40, 60, 120 and 180, postprandial energy expenditure was measured for 15 minutes at each time point

    Time frame: 4 hours

  3. gastrointestinal symptoms

    At timepoints 0, 20, 40, 60, 120 and 180, gastroinstinal symptoms were assessed using a questionnaire

    Time frame: 3 hours

07

Study locations

1 site
  • Purdue University
    West Lafayette, Indiana 47907, United States
08

References and documents

Publications

  • Anguah KO, Wonnell BS, Campbell WW, McCabe GP, McCrory MA. A blended- rather than whole-lentil meal with or without alpha-galactosidase mildly increases healthy adults' appetite but not their glycemic response. J Nutr. 2014 Dec;144(12):1963-9. doi: 10.3945/jn.114.195545. Epub 2014 Oct 8. PubMed 25411033 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 10, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02110511
Lead sponsor
Purdue University
Responsible party
Megan McCrory (Principal investigator, Purdue University) — Principal investigator
First posted
Apr 10, 2014
Start date
Aug 2011
Primary completion
Oct 2012
Completion
Oct 2012
Last update
Apr 10, 2014

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2014. You cannot join it, but the record below documents what was studied.

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