An observational study in Neuromuscular Diseases, sponsored by Centre d'Investigation Clinique et Technologique 805. Status unknown at 2 sites in France. Open to participants aged 6 Years to 70 Years. Per ClinicalTrials.gov, last updated 2018-01-25.
Sponsored by Centre d'Investigation Clinique et Technologique 805 · Observational
The main objective is prospectively study the upper airways function in an adult population of neuromuscular patients. The main measurement will be the evolution of tongue strength recorded each year during annual clinical evaluation on a 5 years period.
The main objective is to study the function of the superior airways (tongue and pharynx) in an non invasive way in neuromuscular patients followed in the home ventilation unit of the Raymond POINCARE hospital (myopathy, neuropathy, disease of the neuromuscular junction or anterior horn) or of Necker Hospital and to detect prematurely the bulbar dysfunction.
The secondary objectives of this prospective monocentric observational physiopathological study are:
The maximal tongue strength protrusion will be measured according to a method already used in the laboratory to explore sleep apnea syndromes.
Swallowing will be estimated by a non invasive method already used to highlight swallowing disorders in neurological and muscular pathologies This method will be associated with a method of recording of thoracic and abdominal movements.
Data wil be compared to a control database obtained for a previous study
300 studies on the registry are indexed under Neuromuscular Diseases; 87 are open to participants now.
This study's planned enrollment of 100 is above the median of 77 across 121 observational studies indexed under Neuromuscular Diseases.
Browse Neuromuscular Diseases studies →Centre d'Investigation Clinique et Technologique 805 is the lead sponsor of 74 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
patients affected by neuromuscular pathology
Exclusion Criteria:
Patients affected by neuromuscular pathology will be explored by tongue strength measurement, respiratory function measurement, swallowing tests and Magnetic resonance imaging
Procedure: tongue strength measurement · Procedure: respiratory function measurement · Procedure: swallowing tests · Other: Magnetic resonance imaging
tongue strength measurement
respiratory function measurement
swallowing tests
Magnetic resonance imaging
Change of tongue strength measurement
Measurement using mechanical force transducer
Time frame: 5 years
swallowing tests
Non invasive measurement of swallowing function using surface electromyography, accelerometry and inductance plethysmography
Time frame: 5 years
Respiratory parameters
Vital capacity and respiratory muscle strength measurement using spirometry and manometry
Time frame: 5 years
Vital capacity
Spirometry
Time frame: 5 years
Respiratory muscle strength
manometry (maximal inspiratory pressure and expiratory pressure)
Time frame: 5 years
This study is status unknown, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.
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Centre d'Investigation Clinique et Technologique 805