CClinicalTrials.gg
CompletedNCT02040753Updated Feb 1, 2016

The Effect of Repeated Lifestyle Intervention on Weight Loss Maintenance

An observational study in Obesity and Overweight, sponsored by University of Copenhagen. Completed at 1 site in Denmark. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-02-01.

Sponsored by University of Copenhagen · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
2,120
Ages
18 Years to 65 Years
Sex
All
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Study summary

In Denmark and the western world, there is an increasing prevalence of obesity probably due to a combination of inadequate daily physical activity and a high energy intake. One approach to achieve weight loss and change life style is to participate in an intensive supervised prolonged life style modification course. The immediate effect is often positive, but over time the overall effect is limited as the majority will not maintain weight loss and a changed life style.

In this study we will analyse the results of the intensive lifestyle intervention as it has been practised at Ubberup Folk High School over the last 13 years. As some people have several stays at Ubberup Folk High School we want to we have a special interest in the effect of repeated lifestyle intervention.

Research question:

What is the effect of several lifestyle interventions on weight loss maintenance?

The study design is retrospective and descriptive and will be based on a lifestyle intervention, as it has practiced in a real life setting at Ubberup folk high school.

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Conditions studied

  • Obesity
  • Overweight

Keywords

  • Lifestyle intervention
  • Change of body composition
  • Physical activity
  • Weight loss maintenance
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In context

Overweight

3,670 studies on the registry are indexed under Overweight; 850 are open to participants now.

This study's enrollment of 2,120 is above the median of 150 across 436 observational studies indexed under Overweight.

Browse Overweight studies →

Lead sponsor

University of Copenhagen is the lead sponsor of 450 studies on the registry; 61 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Former participants of Ubberup Folk High School.

Inclusion criteria

  • Former participants of the intensive lifestyle intervention at Ubberup Folk High School.

Exclusion criteria

Exclusion Criteria:

  • Gastric bypass surgery or banding
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
2,120 participants (actual)
Patient registry
No

Groups and cohorts

  • Intensive Lifestyle Intervention

    Former participants of intensive lifestyle intervention at Ubberup Folk High School.

    Behavioral: Intensive Lifestyle Intervention

Interventions

  • BehavioralIntensive Lifestyle Intervention

    Intensive Lifestyle intervention at Ubberup Folk High School for 10-14 weeks. Daily exercise for 1-3hrs. Calorie restriction. Education within Nutrition, exercise and healthy living in general.

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What researchers measure

Primary outcomes

  1. Change in total body weight

    Time frame: Before intervention, after intervention (after 10-14 weeks) and follow up measurements after 1-13 years depending on when the lifestyle intervention took place

Secondary outcomes

  1. Change in body composition

    Measured by bio-impedance.

    Time frame: Before intervention, after intervention (after 10-14 weeks) and follow up measurements after 1-13 years depending on when the lifestyle intervention took place

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Study locations

1 site
  • University of Copenhagen, Department of Biomedical Sciences
    Copenhagen, 2200, Denmark
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References and documents

Publications

  • Karlsen TI, Sohagen M, Hjelmesaeth J. Predictors of weight loss after an intensive lifestyle intervention program in obese patients: a 1-year prospective cohort study. Health Qual Life Outcomes. 2013 Oct 3;11:165. doi: 10.1186/1477-7525-11-165. PubMed 24090083 ↗
  • McCormack SE, McCarthy MA, Harrington SG, Farilla L, Hrovat MI, Systrom DM, Thomas BJ, Torriani M, McInnis K, Grinspoon SK, Fleischman A. Effects of exercise and lifestyle modification on fitness, insulin resistance, skeletal muscle oxidative phosphorylation and intramyocellular lipid content in obese children and adolescents. Pediatr Obes. 2014 Aug;9(4):281-91. doi: 10.1111/j.2047-6310.2013.00180.x. Epub 2013 Jun 25. PubMed 23801526 ↗
  • Danielsen KK, Svendsen M, Maehlum S, Sundgot-Borgen J. Changes in body composition, cardiovascular disease risk factors, and eating behavior after an intensive lifestyle intervention with high volume of physical activity in severely obese subjects: a prospective clinical controlled trial. J Obes. 2013;2013:325464. doi: 10.1155/2013/325464. Epub 2013 Apr 22. PubMed 23710347 ↗
  • Bruun JM, Helge JW, Richelsen B, Stallknecht B. Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects. Am J Physiol Endocrinol Metab. 2006 May;290(5):E961-7. doi: 10.1152/ajpendo.00506.2005. Epub 2005 Dec 13. PubMed 16352667 ↗
  • Pedersen JO, Zimmermann E, Stallknecht BM, Bruun JM, Kroustrup JP, Larsen JF, Helge JW. [Lifestyle intervention in the treatment of severe obesity]. Ugeskr Laeger. 2006 Jan 9;168(2):167-72. Danish. PubMed 16403343 ↗
  • Bruun JM, Stallknecht B, Helge JW, Richelsen B. Interleukin-18 in plasma and adipose tissue: effects of obesity, insulin resistance, and weight loss. Eur J Endocrinol. 2007 Oct;157(4):465-71. doi: 10.1530/EJE-07-0206. PubMed 17893261 ↗
  • Christiansen T, Bruun JM, Madsen EL, Richelsen B. Weight loss maintenance in severely obese adults after an intensive lifestyle intervention: 2- to 4-year follow-up. Obesity (Silver Spring). 2007 Feb;15(2):413-20. doi: 10.1038/oby.2007.530. PubMed 17299115 ↗
  • Dandanell S, Skovborg C, Praest CB, Kristensen KB, Nielsen MG, Lionett S, Jorgensen SD, Vigelso A, Dela F, Helge JW. Maintaining a clinical weight loss after intensive lifestyle intervention is the key to cardiometabolic health. Obes Res Clin Pract. 2017 Jul-Aug;11(4):489-498. doi: 10.1016/j.orcp.2016.09.009. Epub 2016 Oct 5. PubMed 27720417 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 1, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02040753
Lead sponsor
University of Copenhagen
Collaborators
Ubberup Folk High School
Responsible party
Jørn Wulff Helge (Associate Professor, University of Copenhagen) — Principal investigator
First posted
Jan 20, 2014
Start date
Feb 2014
Primary completion
Jun 2015
Completion
Jan 2016
Last update
Feb 1, 2016

Study contacts

Jørn W Helge, PhD
principal investigator · University of Copenhagen, Department of Biomedical Sciences

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2016. You cannot join it, but the record below documents what was studied.

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