An interventional study of Paracetamol and Placebo in Healthy Young Adults and Physiology, sponsored by University of Copenhagen. Recruiting at 2 sites in Denmark. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-15.
Sponsored by University of Copenhagen · Not applicable, Interventional, and Basic science
The study aim is to determine whether acute inhibition of endogenous prostaglandin synthesis by paracetamol affects the release of gut hormones, glucose absorption and glycemia in healthy young individuals
University of Copenhagen is the lead sponsor of 466 studies on the registry; 64 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
The protein in red blood cells that carries oxygen. A low level is anaemia, which can cause tiredness and breathlessness. Measured in g/dL or g/L (9 g/dL is 90 g/L).
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hemoglobin (Hb)
The protein in red blood cells that carries oxygen. A low level is anaemia, which can cause tiredness and breathlessness. Measured in g/dL or g/L (9 g/dL is 90 g/L).
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Paracetamol
Other: Placebo
Paracetamol is used as a tool to block prostaglandin synthesis
A placebo will be administered to be able to determine the effect of paracetamol on prostaglandin synthesis
Glucagon-like peptide 1
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
Glucose
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
Gastrin
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
Cholecystokinin
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
Glucose-dependent insulinotropic polypeptide (GIP)
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
C-peptide
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
Glucagon
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
Pancreatic polypeptide
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
3-OMG
Plasma concentration
Time frame: From baseline samples (-15, 0 min) until the end of the meal test at t = 180min
Plan to share: No
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