An interventional study of Primary Percutaneous Coronary Intervention in Coronary Artery Disease and Myocardial Infarction, sponsored by John Pernow. Completed at 3 sites in Sweden. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-02-09.
Sponsored by John Pernow · Not applicable, Interventional, and Treatment
See above. 3 patients left to include.
5,598 studies on the registry are indexed under Coronary Artery Disease; 957 are open to participants now.
This study's planned enrollment of 120 is close to the median of 124 across 3,436 interventional studies indexed under Coronary Artery Disease.
Browse Coronary Artery Disease studies →This is the only study on the registry with John Pernow as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Remote conditioning is induced by inflation of a blood pressure cuff around the left thigh to 200 mmHg or 20 mmHg above systolic blood pressure (if \>180 mmHg) for 5 min followed by deflation for 5 min. At least one of these conditioning cycles is performed before PCI is initiated. If time allows, cycles of remote conditioning (5 min leg ischemia and 5 min reperfusion) are repeated until PCI is performed. Following reperfusion, defined as first balloon inflation, four additional cycles of remote conditioning will be performed.
Procedure: Primary Percutaneous Coronary Intervention
The sham procedures include application of the cuff around the thigh but it is not inflated. Otheriwize normal primary PCI.
Procedure: Primary Percutaneous Coronary Intervention
Primary Percutanous Coronary Intervention is performed in both Groups.
Myocardial infarct size expressed as a percentage of the myocardium at risk determined by Cardiac Magnetic Resonance
Time frame: 4-7 days following index event
Myocardial infarct size expressed as a percentage to the myocardium at risk determined by Cardiac Magnetic Resonance
Time frame: 6 months following index event
Global left ventricular function determined by left ventricular ejection fraction determined by CMR.
Time frame: 4-7 days and 6 months following index event
Microvascular obstruction determined by CMR
Time frame: 4-7 days following index event
Quantified ECV (extracellular volume) in left ventricular as myocardium at risk
Time frame: 4-7 days following index event
Myocardial infarct size by CMR expressed as a percentage to the myocardium at risk determined by Bari or modified Approach Score with coronary angiography.
Time frame: 5-7 days following index event
This study is completed, as verified in Feb 2016. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.