An interventional study of Rey figure test and MRI in Alzheimer's Disease and Lewy Body's Dementia, sponsored by University Hospital, Strasbourg, France. Status unknown at 1 site in France. Open to participants aged 45 Years and older. Per ClinicalTrials.gov, last updated 2013-11-25.
Sponsored by University Hospital, Strasbourg, France · Not applicable, Interventional, and Diagnostic
Alzheimer's disease (AD) and Lewy body's dementia (LBD) are two frequent neurodegenerative pathologies. They differ in their expression, their evolution but share same features which make their diagnosis uneasy.
Constructional apraxia has been described in both disease.The underlying mechanisms have been less studied and could be different in AD and LBD.
The definition of the constructional apraxia is purely descriptive and few models are inconclusive.
It is admitted that drawing tasks involve visuo-perceptive and visuo-spatial abilities, executive functions and working memory as well as purely "constructive" skills.
Regarding to different studies, visuo-perceptive abilities are more severely impaired in LBD than in AD and are considered as an early onset sign of the disease.
Executive functions deficits are documented in AD and LDB and could contribute to the drawing impairment.
It is possible to compensate the planning disorders in giving patient the best strategy to use.
If drawing impairment persists, they should result of others mechanisms like visuo-perception, visuo-spatial or constructive deficits.
The investigators suggest that giving the best planning strategy will help more AD patients who are supposed to fail in raison of an executive impairment, than the LDB group who is supposed to present visuo-perceptive deficits. An MRI will be proposed to study the cerebral areas involved in constructional apraxia.
3,765 studies on the registry are indexed under Alzheimer Disease; 881 are open to participants now.
This study's planned enrollment of 80 is above the median of 68 across 2,861 interventional studies indexed under Alzheimer Disease.
Browse Alzheimer Disease studies →University Hospital, Strasbourg, France is the lead sponsor of 989 studies on the registry; 348 are open to participants now.
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Exclusion Criteria:
Rey figure test and MRI
Other: Rey figure test · Other: MRI
Rey figure test and MRI
Other: Rey figure test · Other: MRI
Score obtained at the Rey figure test with a planning strategy help by LBD patients compared to the score obtained by AD patients.
Time frame: At inclusion
The record gives a start of Oct 2013, a primary completion of Nov 2016 and a completion of Nov 2016. It does not say whether these dates are actual or estimated.
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This study is status unknown, as verified in Nov 2013. You cannot join it, but the record below documents what was studied.
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University Hospital, Strasbourg, France →