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CompletedNCT01992302Updated Nov 25, 2013

Risk Factors for Development of Rapid Cycling in Bipolar Disorder Patients

An observational study in Bipolar Disorder, sponsored by Hospital Clinic of Barcelona. Completed at 1 site in Spain. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2013-11-25.

Sponsored by Hospital Clinic of Barcelona · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
289
Ages
18 Years to 80 Years
Sex
All
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Study summary

In this study we tried to elucidate the factors associated with the development of a rapid cycling course in bipolar disorder patients, in a prospective and longitudinal design, and the role of antidepressants. The identification of risk factors is extremely relevant from the clinical point of view. We hypothesized that rapid cycling bipolar disorder is associated with more chronicity, poor outcome, and more antidepressant prescription.

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Conditions studied

  • Bipolar Disorder

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Keywords

  • Rapid cycling
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In context

Bipolar Disorder

1,601 studies on the registry are indexed under Bipolar Disorder; 254 are open to participants now.

This study's enrollment of 289 is above the median of 160 across 329 observational studies indexed under Bipolar Disorder.

Browse Bipolar Disorder studies →

Lead sponsor

Hospital Clinic of Barcelona is the lead sponsor of 319 studies on the registry; 55 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Bipolar I and II disorder patients

Inclusion criteria

  • Bipolar I and II disorder patients according to DSM-IV criteria

Exclusion criteria

Exclusion Criteria:

  • Major medical comorbidities, voluntary drop-out from study
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
289 participants (actual)
Patient registry
No

Groups and cohorts

  • Rapid Cycling Group

    Patients who develop a rapid cycling course during the follow-up period.

  • Non Rapid Cycling Group

    Patients who do not develop a rapid cycling course during the follow-up period.

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What researchers measure

Primary outcomes

  1. Number of patients who develop rapid cycling

    Time frame: 8 years

Secondary outcomes

  1. Factors associated with the development of a rapid cycling course in bipolar disorder patients

    Time frame: 8 years

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Study locations

1 site
  • Barcelona Bipolar Disorders Program, Hospital Clinic Barcelona
    Barcelona, Catalonia 08037, Spain
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 25, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01992302
Lead sponsor
Hospital Clinic of Barcelona
Responsible party
Marc Valenti (MD, PhD, Hospital Clinic of Barcelona) — Principal investigator
First posted
Nov 25, 2013
Start date
Jun 2004
Primary completion
Nov 2013
Completion
Nov 2013
Last update
Nov 25, 2013
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2013. You cannot join it, but the record below documents what was studied.

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