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CompletedNCT01979068Updated Nov 8, 2013

Vascular Inflammation Stratified by Body Size Phenotype

An observational study in Atherosclerosis, Obesity and Metabolic Syndrome, sponsored by Korea University. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-11-08.

Sponsored by Korea University · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
250
Ages
20 Years to 80 Years
Sex
All
01

Study summary

  • Vascular Inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. 18FDG-PET is a promising novel tool for identifying and quantifying vascular inflammation within atherosclerotic plaque
  • Recently, unique subsets of obese individuals, such as metabolically obese but normal weight (MONW) and metabolically healthy obese (MHO), have been getting an attention
  • Therefore, the purpose of this study is to examine the relationship of vascular inflammation,measured by FDG-PET, with various body sized phenotypes
02

Conditions studied

  • Atherosclerosis
  • Obesity
  • Metabolic Syndrome
03

In context

Atherosclerosis

1,567 studies on the registry are indexed under Atherosclerosis; 265 are open to participants now.

This study's enrollment of 250 is above the median of 223 across 571 observational studies indexed under Atherosclerosis.

Browse Atherosclerosis studies →

Lead sponsor

Korea University is the lead sponsor of 64 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Healthy volunteers who underwent a medical health check in the health promotion center in Korea University Guro Hospital

Inclusion criteria

  • Healthy patients for visiting routine medical check in our clinic

Exclusion criteria

Exclusion Criteria:

  • history of CVD (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
  • stage 2 hypertension (resting blood pressure, ≥160/100 mmHg)
  • history of inflammatory conditions that affect the study results
  • taking medications that might affect inflammatory status, including steroid and non-steroidal anti-inflammatory drug within 6 months
  • or malignancy or severe renal or hepatic disease
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
250 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. max TBR values stratified by the four body size phenotypes

    Time frame: 12 weeks

Secondary outcomes

  1. Framingham risk scores according to the four body size phenotypes

    Time frame: 12 weeks

07

Study locations

1 site
  • Korea University Guro Hospital
    Seoul, Korea, Republic of
08

References and documents

Publications

  • Yoo HJ, Kim S, Hwang SY, Hong HC, Choi HY, Seo JA, Kim SG, Kim NH, Choi DS, Baik SH, Choi KM. Vascular inflammation in metabolically abnormal but normal-weight and metabolically healthy obese individuals analyzed with (1)(8)F-fluorodeoxyglucose positron emission tomography. Am J Cardiol. 2015 Feb 15;115(4):523-8. doi: 10.1016/j.amjcard.2014.11.036. Epub 2014 Nov 29. PubMed 25529544 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 8, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01979068
Lead sponsor
Korea University
Responsible party
K. M. Choi (Professor, Korea University) — Principal investigator
First posted
Nov 8, 2013
Start date
Mar 2008
Primary completion
Mar 2011
Last update
Nov 8, 2013

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2013. You cannot join it, but the record below documents what was studied.

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