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CompletedNCT01963000Updated Oct 16, 2013

Standardized Emergency Care for Community Acquired Pneumonia (CAP)

An observational study in Community Acquired Pneumonia, Pneumonia and Infection, sponsored by Klinikum Nürnberg. Completed at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-10-16.

Sponsored by Klinikum Nürnberg · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
2,819
Ages
18 Years and older
Sex
All
01

Study summary

Community acquired pneumonia (CAP) is associated with a high in-hospital mortality. Standardization of diagnostics and adherence to sepsis bundles in the emergency department (ED) are associated with reduced mortality in patients with sepsis. Investigators examined whether the introduction of standardized care bundles and check lists in the ED are associated with a reduced mortality rate in patients hospitalized for CAP.

This is an observational trial. The investigators retrospectively analyzed performance indicators of 2819 consecutive patients with CAP admitted to the Nuremberg Hospital, Germany, from 2008 to 2009. At the turn of the year, implementation of CAP care bundles took place including interprofessional education, checklists and institutionalized feedback. Primary endpoint was in-hospital mortality of CAP patients. After the implementation of CAP care bundles in the ED, mortality of affected patients was significantly lower in 2009 compared to 2008. This study should demonstrate that the implementation of a standardized CAP care bundle in the ED is associated with a risk reduction in affected patients. Standardization of diagnostic and therapeutic processes in the ED therefore improves the outcome of patients hospitalized for CAP.

02

Conditions studied

  • Community Acquired Pneumonia
  • Pneumonia
  • Infection

Keywords

  • Community Acquired Pneumonia
  • Emergency Department
  • Standardized Care
  • Reduced Mortality
  • CRB-65 Risk Classes
  • Antibiotic Therapy
03

In context

Pneumonia

2,044 studies on the registry are indexed under Pneumonia; 283 are open to participants now.

This study's enrollment of 2,819 is above the median of 203 across 688 observational studies indexed under Pneumonia.

Browse Pneumonia studies →

Lead sponsor

Klinikum Nürnberg is the lead sponsor of 10 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Emergency department patients

Inclusion criteria

  • all patients with community acquired pneumonia

Exclusion criteria

Exclusion Criteria:

  • exacerbation of chronic obstructive pulmonary disease
  • malignancy
  • immunosuppression
  • neutropenia
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
2,819 participants (actual)
Patient registry
No

Groups and cohorts

  • CAP

    A patient with CAP was identified by encoding pneumonia without severe immunosuppression (HIV infection, solid organ or bone marrow/stem cell transplants, severe neutropenia) as the main diagnosis (ICD 10 GM) of hospital admission.

06

What researchers measure

Primary outcomes

  1. mortality of CAP patients

    Time frame: up to 14days

Secondary outcomes

  1. mortality up to 14days in subgroups

    Mortality of patients upt to 14day is determined in subgroups (different age groups, sub-groups of CRB-risk classes) CRB-65: C mental confusion; R respiratory rate ≥30/min; B systolic blood pressure \<90 mm Hg; 65, age ≥65 years

    Time frame: up to 14 days

07

Study locations

1 site
  • City Hospital Nuremberg
    Nuremberg, Bavaria 90419, Germany
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 16, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01963000
Lead sponsor
Klinikum Nürnberg
Responsible party
Prof. Dr. Michael Christ (Prof. Dr. med. Michael Christ, Klinikum Nürnberg) — Principal investigator
First posted
Oct 16, 2013
Start date
Jan 2007
Primary completion
Dec 2012
Completion
Dec 2012
Last update
Oct 16, 2013

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Oct 2013. You cannot join it, but the record below documents what was studied.

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