An interventional study of Dexmedetomidine and no dexmedetomidine in Acute Renal Injury, sponsored by Gachon University Gil Medical Center. Completed at 1 site in Korea, Republic of. Open to participants aged 1 Year to 6 Years. Per ClinicalTrials.gov, last updated 2016-11-10.
Sponsored by Gachon University Gil Medical Center · Not applicable, Interventional, and Prevention
we hypothized dexmedetomidine could reduce the reduction of renal function after cardiopulmonary bypass weaning in pediatric patients
dexmedetomidine, a2-adrenoreceptor agonist has been used for sedation or hemodynamic stability for operative procedure. It had been already reported that dexmedetomidine reduce the impairment of renal functon after cardiac operation in adult. we hypothized dexmedetomidine could reduce the reduction of renal function after cardiopulmonary bypass weaning in pediatric patients
1,595 studies on the registry are indexed under Acute Kidney Injury; 371 are open to participants now.
This study's enrollment of 30 is below the median of 100 across 763 interventional studies indexed under Acute Kidney Injury.
Browse Acute Kidney Injury studies →Gachon University Gil Medical Center is the lead sponsor of 88 studies on the registry; 3 are open to participants now.
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Exclusion Criteria:
no administration of dexmedetomidine
Drug: no dexmedetomidine
administration of 0.5ug/kg dexmedetomidine for 10 min and infusion of 0.5ug/kg/h of dexmedetomidine until weaning of cardiopulmonary bypass
Drug: Dexmedetomidine
administration of dexmedetomidine on dexemedetomidine group
Also known as: administration of dexmedetomidine
no administration of dexmedetomidine on control group
Also known as: no administration of dexmedetomidine
renal function
at immediate after anesthetic induction (baseline), after weaning of cardiopulmonary bypass, 2h after end of operationCPB, sodium and creatinine in the urine and serum, N-acetyl-b-glucosaminidase (NAG)and albumin in only urine could be studied
Time frame: from anesthetic induction up to postoperative 2h
Plan to share: Undecided
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Gachon University Gil Medical Center