CClinicalTrials.gg
Status unknownNCT01918982ANOPEC3Updated Aug 8, 2013

Circulating Endothelial Progenitor Cells and Aortic Aneurysm

An observational study in - Aortic Aneurysm, sponsored by Hopital Jean Minjoz. Status unknown. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2013-08-08.

Sponsored by Hopital Jean Minjoz · Observational

The sponsor has not verified this record recently (last verified Aug 2013), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
40
Ages
18 Years to 85 Years
Sex
All
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Study summary

We aimed to see if aortic aneurysms could be followed-up by circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- blood level.

Read the detailed description

Circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- have been shown to be inversely correlated to aortic aneurysm size. We aimed to see if aortic aneurysms could be followed-up by circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- blood level. 40 patients followed for known aortic aneurysm >30mm and \<50mm will be followed up every 6 months during 2 years. Each 6 months they will have a consultation by their physiologist with an echo or a CT-scan. At the same time, a 10ML blood sample will be taken to assess the circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- blood level.

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Conditions studied

  • - Aortic Aneurysm

Keywords

  • Aortic aneurysm
  • circulating endothelial progenitor cells
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In context

Aneurysm

960 studies on the registry are indexed under Aneurysm; 175 are open to participants now.

This study's planned enrollment of 40 is below the median of 151 across 443 observational studies indexed under Aneurysm.

Browse Aneurysm studies →

Lead sponsor

Hopital Jean Minjoz is the lead sponsor of 5 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with aortic aneurysm

Inclusion criteria

  • Aortic aneurysm size >30mm and > 50mm

Exclusion criteria

Exclusion Criteria:

  • Infectious disease
  • Inflammatory disease
  • Liver insuffisency
  • Cancer evolutive
  • Pregnant women
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
40 participants (estimated)
Patient registry
No

Groups and cohorts

  • Aortic aneurysm

    Patients with aortic aneurysm \>30mm and \< 50mm

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What researchers measure

Primary outcomes

  1. Circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- blood concentration

    Patients are followed for 2 years

    Time frame: 2 years

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Parietti E, Pallandre JR, Deschaseaux F, Aupecle B, Durst C, Kantelip JP, Chocron S, Davani S. Presence of circulating endothelial progenitor cells and levels of stromal-derived factor-1alpha are associated with ascending aorta aneurysm size. Eur J Cardiothorac Surg. 2011 Jul;40(1):e6-12. doi: 10.1016/j.ejcts.2011.02.065. Epub 2011 Apr 9. PubMed 21481600 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 8, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01918982
Lead sponsor
Hopital Jean Minjoz
Responsible party
Prof. Sidney Chocron (MD, PhD, Hopital Jean Minjoz) — Principal investigator
First posted
Aug 8, 2013
Start date
Oct 2013
Primary completion
Feb 2016 (estimated)
Completion
May 2016 (estimated)
Last update
Aug 8, 2013

Study contacts

Sidney Chocron
Contact
sidney.chocron@univ-fcomte.fr
+33381533121
Sidney Chocron, MD, PhD
principal investigator · Université de Franche-comté. France
Andrea Perrotti, MD
principal investigator · Université de Franche-Comté. France
Simon Rinckenbach, MD, PhD
principal investigator · Université de Franche-Comté. France
Siamak Davani, MD, PhD
principal investigator · Université de Franche-Comté. France

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Aug 2013. You cannot join it, but the record below documents what was studied.

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