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CompletedNCT01872325Updated Mar 17, 2021Results posted

Improving Cardiac Arrest Diagnostic Accuracy of Emergency Medical Dispatchers

An observational study in Cardiac Arrest, sponsored by Ottawa Hospital Research Institute. Completed at 1 site in Canada. Open to participants aged 16 Years and older. Per ClinicalTrials.gov, last updated 2021-03-17.

Sponsored by Ottawa Hospital Research Institute · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
1,076
Ages
16 Years and older
Sex
All
01

Study summary

The main goal of this project is to help 9-1-1 emergency medical dispatchers save the lives of more cardiac arrest victims. The investigators will develop teaching tools to help the dispatchers recognize abnormal breathing that may indicate a victim as having a cardiac arrest. After training sessions, the investigators will see if dispatchers can get better at recognizing abnormal breathing, how often they give CPR instructions, and if use of the teaching tool will increase bystander CPR and the number of victims leaving the hospital alive.

Read the detailed description

Cardiac arrest is a leading cause of death in Canada; it is defined as the sudden cessation of cardiac mechanical activity. It is uniformly fatal if not treated within minutes. More than 85% of out-of-hospital cardiac arrest (OOHCA) occur in residential locations so public access to automatic external defibrillators, to restart the heart, are not helpful. The overall rate of survival for OOHCA rarely exceeds 8%.

Bystander cardiopulmonary resuscitation (CPR) is chest compression and ventilations provided by someone not on the emergency response team. A victim or cardiac arrest is almost 4 times more likely to survive when receiving bystander CPR. However, despite various attempts to improve bystander rates they have remained low, not exceeding 15% in Ontario. It has been shown that since the ambulance dispatch centres in Ontario implemented dispatch-assisted CPR instructions (given to callers while emergency vehicles were on the way), there was a significant increase in use.

Emergency medical dispatchers can identify about 70% of OOHCA cases over the phone. Agonal breathing (laboured breathing preceding death) may be misinterpreted as a sign of life, and is responsible for as much as 50% of missed diagnoses. There is no specific training on the significance of this sign, and minimal information about recognizing cardiac arrest. An educational intervention designed to better understand the significance of agonal breathing and to clarify the existing CPR instruction protocol will most likely increase the frequency of CPR instructions, bystander CPR rates, and potentially survival of victims of cardiac arrest.

02

Conditions studied

  • Cardiac Arrest

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Keywords

  • cardiac arrest
  • bystander cardiopulmonary resuscitation CPR
  • dispatch-assisted CPR instructions
  • agonal breathing
03

In context

Heart Arrest

966 studies on the registry are indexed under Heart Arrest; 226 are open to participants now.

This study's enrollment of 1,076 is above the median of 200 across 382 observational studies indexed under Heart Arrest.

Browse Heart Arrest studies →

Lead sponsor

Ottawa Hospital Research Institute is the lead sponsor of 538 studies on the registry; 100 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
16 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

All patients with out-of-hospital cardiac arrest

Inclusion criteria

  • presumed cardiac origin
  • event occurs in the catchment area of Training or Control Site
  • resuscitation is attempted by a bystander and/or the emergency responders

Exclusion criteria

Exclusion Criteria:

  • patients younger than 16 years old
  • patients who are "obviously dead" as defined by the Ambulance Act of Ontario (decomposition, rigor mortis, decapitation, or other)
  • trauma victims including hanging and burns
  • cardiac arrest of non-cardiac origin including drug overdose, carbon monoxide poisoning, drowning, exsanguination, electrocution, asphyxia, hypoxia related to respiratory disease, cerebrovascular accident, and documented terminal illness
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
1,076 participants (actual)

Groups and cohorts

  • Training site

    All emergency medical dispatchers at a central ambulance communication centre in Ontario will participate in an educational program designed to improve cardiac arrest diagnostic accuracy.

    Behavioral: Education

  • Control site

    All emergency medical dispatchers at a central ambulance communications centre geographically remote from the Training Site and has a similar rate to the Training Site for cardiac arrests, bystander CPR rate, and survival

Interventions

  • BehavioralEducation

    An education program will be developed using behaviour change techniques specifically mapped to address modifiable factors identified in a previous study. These techniques will include: information about the significance of agonal breathing, modeling/demonstration of desired behavioural skills, rehearsal of desired skills, and monitoring/reinforcement and feedback.

06

What researchers measure

Primary outcomes

  1. Number of Participants With Agonal Breathing

    By reviewing recordings of all cardiac arrest calls, including missed cases retrieved from a registry, document presence or absence of agonal breathing.

    Time frame: At the time of the cardiac arrest event

Secondary outcomes

  1. Number of Cases Where Cardiac Arrest Was Recognized by the Ambulance Dispatcher

    By reviewing recordings of all cardiac arrest calls, collect information on dispatcher recognition of cardiac arrest to bystander implementation of chest compressions

    Time frame: At the time of the cardiac arrest event

Other outcomes

  1. Number of Participants Who Received Bystander CPR

    The first member of the emergency response team to arrive at scene will document whether or not chest compressions have been initiated by someone prior to the arrival of emergency team

    Time frame: At the time of the cardiac arrest event

  2. Number of Participants Surviving to Hospital Discharge

    Accessing hospital medical records or coroner's reports, assess survival of cardiac arrest victim as being discharged alive from hospital

    Time frame: At the time of the cardiac arrest event to discharge alive from hospital (varies, depending on length of hospital stay)

07

Results

Posted Nov 24, 2020

Participant flow

Participant flow — Overall Study
MilestoneTraining SiteControl Site
Started689387
Completed689387
Not completed00

Outcome measures

PrimaryNumber of Participants With Agonal Breathing

By reviewing recordings of all cardiac arrest calls, including missed cases retrieved from a registry, document presence or absence of agonal breathing.

Time frame:
At the time of the cardiac arrest event
Reported as:
Count of participants · Participants
Number of Participants With Agonal Breathing
ParticipantsTraining SiteControl Site
Number of Participants With Agonal Breathing17687
SecondaryNumber of Cases Where Cardiac Arrest Was Recognized by the Ambulance Dispatcher

By reviewing recordings of all cardiac arrest calls, collect information on dispatcher recognition of cardiac arrest to bystander implementation of chest compressions

Time frame:
At the time of the cardiac arrest event
Reported as:
Count of participants · Participants
Number of Cases Where Cardiac Arrest Was Recognized by the Ambulance Dispatcher
ParticipantsTraining SiteControl Site
Number of Cases Where Cardiac Arrest Was Recognized by the Ambulance Dispatcher495287
Other pre-specifiedNumber of Participants Who Received Bystander CPR

The first member of the emergency response team to arrive at scene will document whether or not chest compressions have been initiated by someone prior to the arrival of emergency team

Time frame:
At the time of the cardiac arrest event
Reported as:
Count of participants · Participants
Number of Participants Who Received Bystander CPR
ParticipantsTraining SiteControl Site
Number of Participants Who Received Bystander CPR247153
Other pre-specifiedNumber of Participants Surviving to Hospital Discharge

Accessing hospital medical records or coroner's reports, assess survival of cardiac arrest victim as being discharged alive from hospital

Time frame:
At the time of the cardiac arrest event to discharge alive from hospital (varies, depending on length of hospital stay)
Reported as:
Count of participants · Participants
Number of Participants Surviving to Hospital Discharge
ParticipantsTraining SiteControl Site
Number of Participants Surviving to Hospital Discharge8627

Adverse events

Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Training Site—0/689 (0%)0/689 (0%)
Control Site—0/387 (0%)0/387 (0%)

Baseline characteristics

Age, Continuous
Age, Continuous(years)Training SiteControl SiteTotal
Mean68 (16 to 100)68 (22 to 98)68 (16 to 100)
Sex: Female, Male
Sex: Female, Male(Participants)Training SiteControl SiteTotal
Female217136353
Male472251723
Race and Ethnicity Not Collected
Race and Ethnicity Not Collected(Participants)Training SiteControl SiteTotal
Count of participants——0
Region of Enrollment
Region of Enrollment(participants)Training SiteControl SiteTotal
Canada6893871076
Witnessed Status
Witnessed Status(Participants)Training SiteControl SiteTotal
Count of participants310162472
Initial Cardiac Rhythm Ventricular Fibrillation/Ventricular Tachycardia
Initial Cardiac Rhythm Ventricular Fibrillation/Ventricular Tachycardia(Participants)Training SiteControl SiteTotal
Count of participants19987286
08

Study locations

1 site
  • Ottawa Hospital Research Institute
    Ottawa, Ontario K1Y 4E9, Canada
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 17, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01872325
Lead sponsor
Ottawa Hospital Research Institute
Responsible party
Sponsor
First posted
Jun 7, 2013
Start date
Jun 2013
Primary completion
Sep 2014
Completion
Dec 2014
Results posted
Nov 24, 2020
Last update
Mar 17, 2021

Study contacts

Christian Vaillancourt, MD,MSc,FRCPC
principal investigator · The Ottawa Hospital Research Institute and University of Ottawa

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2021. You cannot join it, but the record below documents what was studied.

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