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CompletedNCT01861275Updated May 24, 2016

Ischaemic Stroke and Sleep Apnea in Northern Part of Finland

An observational study in Sleep Apnoea and Cerebral Palsy, sponsored by University of Oulu. Completed at 1 site in Finland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-05-24.

Sponsored by University of Oulu · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
256
Ages
18 Years and older
Sex
All
01

Study summary

Obstructive sleep apnoea is a risk factor for ischaemic stroke. study hypothesis: In prospective study the investigators want to know how many ischaemic stroke patients have sleep apnoea and does thrombolysis play a role in severity of osa in six months follow up.

Read the detailed description

In prospective study the investigators include all over 18 years old patients who came to emergency room for ischaemic stroke. Exclusion criteria is not able to co-operate or need for intensive care unit.The investigators shall take 100 control patients who have ischaemic stroke and no thrombolysis and 100 study patients who will have thrombolysis. The investigators do sleep registration during hospital staying within 2 days after patients have felt ill.Follow-up registration will be done after 6 months at home.

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Conditions studied

  • Sleep Apnoea
  • Cerebral Palsy

Keywords

  • osa
  • cerebral palsy
  • thrombolysis in cerebral palsy
  • sleep registration
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In context

Apnea

1,422 studies on the registry are indexed under Apnea; 159 are open to participants now.

This study's enrollment of 256 is above the median of 106 across 386 observational studies indexed under Apnea.

Browse Apnea studies →

Lead sponsor

University of Oulu is the lead sponsor of 138 studies on the registry; 21 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

residents of Oulu university hospital area. consecutive patient sampling

Inclusion criteria

  • over 18 years old patients that have cerebral palsy and are able to participate to the study.

Exclusion criteria

Exclusion Criteria:

  • no co-operation and need for intensive care unit
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
256 participants (actual)
Target follow-up
6 Months
Patient registry
Yes

Groups and cohorts

  • Nasal CPAP

    We want to study the nasal-cpap treatment and it's compliance in sleep apnea patients with ischaemic stroke.

    Device: Nasal CPAP

  • no Nasal CPAP

    No nasal-cpap in sleep apnea patients with ischaemic stroke.

Interventions

  • DeviceNasal CPAP

    Nasal CPAP treatment for obstructive sleep apnoea

06

What researchers measure

Primary outcomes

  1. cerebral palsy events and severity of osa

    in prospective study outcome measure is severity of osa in 6months follow-up

    Time frame: from six months to twenty four months

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Study locations

1 site
  • Oulu university hospital,department of neurology
    Oulu, northern Finland 90029, Finland
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References and documents

Publications

  • Huhtakangas JK, Saaresranta T, Vahanikkila H, Huhtakangas J. Nocturnal hypoxemia and central apneas increase mortality, but not recurrent ischemic events after ischemic stroke. Sleep Med. 2022 Sep;97:1-9. doi: 10.1016/j.sleep.2022.05.014. Epub 2022 May 23. PubMed 35679775 ↗
  • Huhtakangas JK, Huhtakangas J, Bloigu R, Saaresranta T. Unattended sleep study in screening for sleep apnea in the acute phase of ischemic stroke. Sleep Med. 2020 Jan;65:121-126. doi: 10.1016/j.sleep.2019.08.002. Epub 2019 Aug 8. PubMed 31751906 ↗
  • Huhtakangas JK, Saaresranta T, Bloigu R, Huhtakangas J. The Evolution of Sleep Apnea Six Months After Acute Ischemic Stroke and Thrombolysis. J Clin Sleep Med. 2018 Dec 15;14(12):2005-2011. doi: 10.5664/jcsm.7524. Erratum In: J Clin Sleep Med. 2020 May 15;16(5):837-838. doi: 10.5664/jcsm.8428. PubMed 30518443 ↗
  • Huhtakangas JK, Huhtakangas J, Bloigu R, Saaresranta T. Prevalence of sleep apnea at the acute phase of ischemic stroke with or without thrombolysis. Sleep Med. 2017 Dec;40:40-46. doi: 10.1016/j.sleep.2017.08.018. Epub 2017 Oct 7. PubMed 29221777 ↗

Individual participant data

Plan to share: Yes — Write a paper.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 24, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01861275
Lead sponsor
University of Oulu
Responsible party
Sponsor
First posted
May 23, 2013
Start date
Apr 2013
Primary completion
Jan 2015
Completion
Jan 2015
Last update
May 24, 2016

Study contacts

Tarja Saaresranta, Md PhD
study director · University hospital of Turku

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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