An interventional study of Early parenteral nutrition and Late parenteral nutrition in Cancer, Abdominal Surgery and Parenteral Nutrition, sponsored by Instituto do Cancer do Estado de São Paulo. Status unknown at 2 sites in Brazil. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-02-07.
Sponsored by Instituto do Cancer do Estado de São Paulo · Not applicable, Interventional, and Treatment
The aim of this study is to find which is the best nutritional strategy in cancer patients undergoing abdominal surgery regarding postoperative complications.
There is a controversy regarding the timing of initiation of parenteral nutrition in cancer patients undergoing abdominal surgery in whom caloric targets cannot be met by enteral nutrition alone.
This is a randomized and controlled trial comparing early initiation with late initiation of parenteral nutrition.
Early-initiation group: patients will be randomized to initiate parenteral nutrition in the 2nd day after surgery.
Late-initiation group: patients will be randomized to initiate parenteral nutrition in the 7th day after surgery.
Calculations regarding the caloric goal included protein energy and were based on corrected ideal body weight, age and sex. When oral or enteral nutrition covered 80% of the calculated caloric goal, parenteral nutrition was reduced and progressively stopped.
Instituto do Cancer do Estado de São Paulo is the lead sponsor of 90 studies on the registry; 23 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Parenteral nutrition starts at 2nd postoperative day.
Dietary Supplement: Early parenteral nutrition
Parenteral nutrition starts at 7th postoperative day.
Dietary Supplement: Late parenteral nutrition
Clinical complications
respiratory, cardiovascular, renal, neurological, infectious, surgical
Time frame: 30 days
Mortality
30-day mortality
Time frame: 30 days
Length of stay in ICU and in hospital
Length of stay
Time frame: 30 days
ICU readmission rate
ICU readmission rate
Time frame: 30 days
Duration of pharmacologic hemodynamic support
duration of vasopressor therapy
Time frame: 30 days
Levels of C-reactive protein
serum levels of C-reactive protein
Time frame: 7 days
Duration of mechanical ventilation
Duration of invasive mechanical ventilation
Time frame: 30 days
Liver dysfunction
liver dysfunction according SOFA
Time frame: 30 days
This study is status unknown, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Instituto do Cancer do Estado de São Paulo