A Phase 3 interventional study of Osteopathic manipulative treatment and sham comparator in Obstructive Sleep Apnea Syndrome, sponsored by Assistance Publique - Hôpitaux de Paris. Completed at 1 site in France. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-01-25.
Sponsored by Assistance Publique - Hôpitaux de Paris · Phase 3, Interventional, and Treatment
The main objective is to evaluate an osteopathic compression of pterygopalatine node in healthy subjects and patients suffering from obstructive apnea syndrome (OSA).
Osteopathic compression will be compared to a sham manoeuvre in a cross over design on apnea hypopnea index, pharyngeal collapsibility and symptoms in patients suffering from OSA, and on symptoms and pharyngeal collapsibility in healthy subjects.
1,423 studies on the registry are indexed under Apnea; 160 are open to participants now.
This study's enrollment of 52 is close to the median of 51 across 966 interventional studies indexed under Apnea.
Browse Apnea studies →Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,505 studies on the registry; 1,006 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Obstructive sleep apnea syndrome patient:
Inclusion criteria :
Exclusion criteria :
Healthy Volunteers
Inclusion criteria :
Exclusion criteria :
Osteopathic compression of pterygopalatine node
Procedure: Osteopathic manipulative treatment
sham Osteopathic pterygopalatine node compression
Procedure: sham comparator
Osteopathic compression of pterygopalatine node
Apnea-hypopnea index
Time frame: 24 hours
Pharyngeal sensitivity test
Time frame: 30 min
Determination of pharyngeal critical pressure
Time frame: 24 hours
Daily clinical symptoms of osa
Time frame: 7 days
Pharyngeal sensitivity test
Time frame: 24 hours
Determination of pharyngeal critical pressure
Time frame: 30 min
Inspiratory nasal pic flow
Time frame: 30 min
Inspiratory nasal pic flow
Time frame: 24 hours
This study is completed, as verified in Jun 2014. You cannot join it, but the record below documents what was studied.
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Assistance Publique - Hôpitaux de Paris