An interventional study of Mueller manoeuvre and Inspiratory threshold in Patients With Paroxysmal Atrial Fibrillation, sponsored by University of Zurich. Completed at 1 site in Switzerland. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2013-12-23.
Sponsored by University of Zurich · Not applicable, Interventional, and Diagnostic
In this randomised controlled cross-over study we will investigate whether intrathoracic pressure changes induced by simulated obstructive apnoea and hypopnoea trigger premature supraventricular and ventricular contractions as well as atrial fibrillation in patients with paroxysmal atrial fibrillation.
2,198 studies on the registry are indexed under Sleep Apnea, Obstructive; 469 are open to participants now.
This study's enrollment of 45 is below the median of 53 across 1,448 interventional studies indexed under Sleep Apnea, Obstructive.
Browse Sleep Apnea, Obstructive studies →University of Zurich is the lead sponsor of 1,030 studies on the registry; 130 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion criteria:
Mueller manoeuvre lasting for 20 seconds
Other: Mueller manoeuvre
One continuous inspiration through an inspiratory threshold load for 20 seconds
Other: Inspiratory threshold
Expiratory apnoea (without respiratory effort) lasting for 20 seconds
Other: Expiratory apnoea
Steady state normal breathing for 20 seconds
Other: Steady state normal breathing
Number of subjects with premature myocardial contractions and/or atrial fibrillation
Time frame: 20 seconds
ECG-derived myocardial de- and repolarization times
Time frame: 20 seconds
This study is completed, as verified in Dec 2013. You cannot join it, but the record below documents what was studied.
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University of Zurich