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WithdrawnNCT01749423Updated Feb 3, 2014

A Retrospective Study to Evaluate the Effectiveness of onabotulinumtoxinA in Preventing Headaches in Patients With Chronic Migraines

An observational study in Chronic Migraine, Headache, sponsored by Allergan. Withdrawn. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2014-02-03.

Sponsored by Allergan · Observational

Why this study was withdrawn
Company decision due to enrollment challenges.
Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
0
Ages
18 Years to 65 Years
Sex
All
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Study summary

This study will evaluate the effectiveness of OnabotulinumtoxinA to prevent headaches in patients with Chronic Migraine.

02

Conditions studied

  • Chronic Migraine, Headache
03

In context

Migraine Disorders

1,528 studies on the registry are indexed under Migraine Disorders; 299 are open to participants now.

Browse Migraine Disorders studies →

Lead sponsor

Allergan is the lead sponsor of 499 studies on the registry; none are open to participants now.

Of its 91 completed or terminated interventional studies of FDA-regulated products, 89 (98%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Participants with chronic migraines who received a minimum of two consecutive treatment cycles of 100 units onabotulinumtoxinA and a minimum of two consecutive treatment cycles with the OnabotulinumtoxinA dosing between 155 and 195 units.

Inclusion criteria

  • History of chronic migraines
  • 15 or more headache days over a 30 day period
  • A minimum of 2 consecutive treatment cycles of 100 units onabotulinumtoxinA and a minimum of 2 consecutive treatment cycles with the onabotulinumtoxinA dosing between 155 and 195 units

Exclusion criteria

Exclusion Criteria:

  • Any treatment cycle dose of onabotulinumtoxinA greater than 200 units
05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
0 participants (actual)

Groups and cohorts

  • All participants

    Previous treatment with onabotulinumtoxinA for Chronic Migraine based on retrospective review of medical records.

    Biological: OnabotulinumtoxinA

Interventions

  • BiologicalOnabotulinumtoxinA

    Previous treatment with onabotulinumtoxinA for Chronic Migraine.

    Also known as: botulinum toxin Type A, BOTOX®

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What researchers measure

Primary outcomes

  1. Number of Headache Days

    Time frame: Up to 56 Weeks

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 3, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01749423
Lead sponsor
Allergan
Responsible party
Sponsor
First posted
Dec 13, 2012
Start date
Nov 2012
Primary completion
Dec 2013 (estimated)
Completion
Dec 2013 (estimated)
Last update
Feb 3, 2014

Study contacts

Medical Director
study director · Allergan

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Jan 2014. You cannot join it, but the record below documents what was studied.

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