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CompletedNCT01748981FALCUpdated Feb 12, 2019

Fitness, Activity and Lung Cancer Study

An interventional study of Physical training and As usual in Lung Cancer, sponsored by Oslo University Hospital. Completed at 1 site in Norway. Open to participants aged 30 Years to 79 Years. Per ClinicalTrials.gov, last updated 2019-02-12.

Sponsored by Oslo University Hospital · Not applicable, Interventional, and Health services research

From the registry’s dates

  • Registered 9 months after the study started (first participant enrolled Nov 2010, registered Aug 2011).
Phase
Not applicable
Study type
Interventional
Enrollment
71
Allocation
Randomized
Ages
30 Years to 79 Years
Sex
All
01

Study summary

The purpose of the study is to investigate the change in pulmonary function and exercise capacity in lung cancer patients after pulmonary resection. Furthermore, to study the effect of training on aerobic capacity, muscular strength, morbidity and survival. Physical activity level by accelerometers, body composition by DXA and quality of life will also be reported.

Read the detailed description

Five year after surgery, all included patients will be reinvited to undergo a fourth health excame to study the long-term effects of exercise training on physical fitness, morbidity and survival.

02

Conditions studied

  • Lung Cancer

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Keywords

  • Pulmonary function
  • Maximal oxygen uptake
  • Cardiorespiratory fitness
  • High-intensity training
  • Surgery
03

In context

Lung Neoplasms

7,243 studies on the registry are indexed under Lung Neoplasms; 1,557 are open to participants now.

This study's enrollment of 71 is above the median of 60 across 5,295 interventional studies indexed under Lung Neoplasms.

Browse Lung Neoplasms studies →

Lead sponsor

Oslo University Hospital is the lead sponsor of 810 studies on the registry; 148 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
30 Years to 79 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Non smal cell lung cancer
  • Patient living in Oslo or Akershus county and accepted for lung cancer surgery at Oslo University hospital and Akershus University hospital
  • were able to read and speak Norwegian

Exclusion criteria

Exclusion Criteria:

  • Mental incompetence or physical disability that makes it difficult to walk on a treadmill
  • Treatment or medical complications affecting ability to participate in an exercise group
  • > 79 years
05

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
71 participants (actual)

Study arms

  • Other
    Physical training

    Exercise intervention.

    Other: Physical training

  • Other
    As usual

    Controls

    Other: As usual

Interventions

  • OtherPhysical training

    Physical training three times a week for 20 week including endurance and strength training compare to the "as usual" group as controls

  • OtherAs usual

    Controls, not training

06

What researchers measure

Primary outcomes

  1. Change in Maximal oxygen uptake (VO2max) from baseline

    Change in VO2max from before to after surgery to measure the effect of surgery, and after six months to measure the effect of high-intensity training intervention, and after five years to study long-term effects

    Time frame: An expected average of two weeks before surgery (baseline), four to six weeks after surgery, after six months and after 5 years

Secondary outcomes

  1. Change in Pulmonary function from baseline

    Change in pulmonary function from before to after surgery and after the intervention

    Time frame: Pulmonary function is measured three times; an expected average of two weeks before surgery, four to six weeks after surgery, after after six months and after five years.

Other outcomes

  1. DXA scan

    Change in body composition from before to after surgery and after the intervention

    Time frame: An expected average of two weeks before surgery, four to six weeks after surgery, after six months and after five years

  2. Quality of life

    Change in quality of life from before to after surgery and after the intervention

    Time frame: Measured three times: An expected average of two weeks before surgery, four to six weeks after surgery, after six months and after five years

  3. Physical activity

    Physical activity will be objectively measured by accelerometers for seven consecutive days to determine change in activity level after surgery

    Time frame: Measured three times: six weeks after surgery, after six months and after five years

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Study locations

1 site
  • Oslo University Hospital
    Oslo, 0450, Norway
08

References and documents

Publications

  • Edvardsen E, Skjonsberg OH, Holme I, Nordsletten L, Borchsenius F, Anderssen SA. High-intensity training following lung cancer surgery: a randomised controlled trial. Thorax. 2015 Mar;70(3):244-50. doi: 10.1136/thoraxjnl-2014-205944. Epub 2014 Oct 16. PubMed 25323620 ↗
  • Edvardsen E, Anderssen SA, Borchsenius F, Skjonsberg OH. Reduction in cardiorespiratory fitness after lung resection is not related to the number of lung segments removed. BMJ Open Sport Exerc Med. 2015 Oct 5;1(1):e000032. doi: 10.1136/bmjsem-2015-000032. eCollection 2015. PubMed 27900127 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 12, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01748981
Lead sponsor
Oslo University Hospital
Collaborators
Norwegian School of Sport Sciences, University Hospital, Akershus, Vestre Viken Hospital Trust
Responsible party
Elisabeth Edvardsen (Prinsipal Investigator, Oslo University Hospital) — Principal investigator
First posted
Dec 13, 2012
Start date
Nov 2010
Primary completion
Dec 2017
Completion
Jun 20, 2018
Last update
Feb 12, 2019

Study contacts

Elisabeth Edvardsen, PhD
principal investigator · Oslo University Hospital

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.

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