A Phase 4 interventional study of Indoor residual spraying with bendiocarb and LLIN by universal coverage campaign in Malaria, sponsored by London School of Hygiene and Tropical Medicine. Status unknown at 1 site in Tanzania. Open to participants aged 6 Months to 14 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-10-03.
Sponsored by London School of Hygiene and Tropical Medicine · Phase 4, Interventional, and Prevention
The study is a cluster randomised trial to compare the effectiveness of indoor residual spraying (IRS) combined with the use of long lasting insecticidal nets (LLINs) with the effectiveness of LLINs alone for preventing malaria infection and morbidity. The primary outcome measure is prevalence of parasitaemia and anaemia in children aged 0.5-10 years, measured in cross sectional surveys. Secondary outcomes include relative population density for each mosquito vector species, malaria transmission as measured by entomological inoculation rates (EIR) by mosquito vector species, monitoring of resistance markers including kdr, and user acceptability of LLINs compared with IRS.
Findings from this study are expected to inform decision making so that resource utilization can be optimised.
1,299 studies on the registry are indexed under Malaria; 86 are open to participants now.
This study's planned enrollment of 22,300 is above the median of 220 across 1,027 interventional studies indexed under Malaria.
Browse Malaria studies →London School of Hygiene and Tropical Medicine is the lead sponsor of 296 studies on the registry; 15 are open to participants now.
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LLIN by universal coverage campaign 2 rounds of indoor residual spraying with bendiocarb insecticide
Other: Indoor residual spraying with bendiocarb · Other: LLIN by universal coverage campaign
LLIN by universal coverage campaign
Other: LLIN by universal coverage campaign
2 rounds of indoor residual spraying with bendiocarb insecticide, 4 months apart
Also known as: Ficam
Long lasting Insecticide treated mosquito net
Also known as: Olyset nets
Prevalence of malarial infection in children 6 months to 10 years
Time frame: 9 months post randomisation
Moderate to severe anaemia in children under 5 years
Time frame: 9 months post randomisation
Post-spraying prevalence of infection with malarial parasites in children 6 months to 10 years
Time frame: 6 months post randomisation
Entomological Innoculation Rate
Time frame: Malaria season post randomisation(Average value during 6 months after randomisation)
Relative abundance of adult Anopheles mosquitoes by species
Time frame: Malaria season post randomisation (Average value during 6 months after randomisation)
genotypic markers of insecticide resistance in malaria vector mosquitoes
Time frame: Malaria season post randomisation (Average value during 6 months after randomisation)
This study is status unknown, as verified in Oct 2012. You cannot join it, but the record below documents what was studied.
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London School of Hygiene and Tropical Medicine