An observational study in Pulmonary Hypertension: Efficacy of Rehabilitation, sponsored by Hannover Medical School. Status unknown at 1 site in Germany. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-08-20.
Sponsored by Hannover Medical School · Observational
Pulmonary hypertension (PH) leads to impaired physical condition (PC), body composition (BC) and health-related quality of life (HRQOL). We hypothesized that a 3 week inpatient pulmonary rehabilitation (PR) improves PC, BC and HRQOL.
Pulmonary hypertension (PH) impairs physical condition (PC), body composition (BC) and health-related quality of life (HRQOL).
Specific pharmacological treatment and - in selected patients, refractory to agents - lung or combined heart and lung transplantation can improve physical functioning and long term survival. Initial trials with limited numbers of patients were encouraging. Investigation of larger cohorts is essential to assess the efficacy of rehabilitation programmes in PH.
We hypothesize that a 3 week inpatient pulmonary rehabilitation (PR) improves PC, BC and HRQOL in patients with PH in functional classes (FC) II and III. Critical ill patients with a functional class IV are excluded. All patients with PH undergo a 3-week inpatient rehabilitation program (interval bicycle and strength training, physiotherapy, psychological support, education). Exercise testing (peak work load (PWL) 6-min-walk distance), body composition (bioimpedance analysis BIA: lean body mass (LBM), body cell mass (BCM), BCM/LBM ratio, phase angle (PA)) and HRQOL (SF 36 questionnaire) are assessed at baseline and completion of PR.
1,105 studies on the registry are indexed under Hypertension, Pulmonary; 234 are open to participants now.
This study's planned enrollment of 100 is below the median of 116 across 386 observational studies indexed under Hypertension, Pulmonary.
Browse Hypertension, Pulmonary studies →Hannover Medical School is the lead sponsor of 198 studies on the registry; 24 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with pulmonary hypertension in World Heart Organization functional classification classes (FC) II and III
Exclusion Criteria:
Exercise capacity
Exercise capacity (peak work load and 6-minute walk distance at completion of an 3-week inpatient pulmonary rehabilitation)
Time frame: 3 weeks
Body composition
Body composition (bioimpedance analysis)
Time frame: 3 weeks
Health related Quality of Life
Health related Quality of Life (Short form 36 questionnaire)
Time frame: 3 weeks
Right ventricular function
Right ventricular function (echocardiography: estimated right ventricular systolic pressure, Tricuspid annular plane systolic excursion, left ventricular eccentricity index)
Time frame: 3 weeks
Activities of daily living
Activities of daily living (Barthel's Index)
Time frame: 3 weeks
This study is status unknown, as verified in Aug 2015. You cannot join it, but the record below documents what was studied.
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Hannover Medical School