An interventional study of Fractional carbon dioxide laser in Freckles, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 10 Years and older. Per ClinicalTrials.gov, last updated 2014-04-07.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Freckles are clusters of melanin in the superficial epidermis. They affect mostly face and sun exposed areas, and appear as flat brown or red macules that fade in winter, usually in a fair complexion patient, but may be present in other skin types.
The gold standard in the industry for non-surgical facial rejuvenation, removal of wrinkles, pigmentation, and general sun damage has been the carbon dioxide (CO2) laser since the mid 1990s. The traditional CO2 laser was very effective, however it fell out of favor because it required general anesthesia. It also had a prolonged recovery time. Over the last several years, advances in technology known as fractional resurfacing has made the CO2 laser popular again: Fractional CO2 laser treatment is one of the newest laser rejuvenation technology. It proved successful in treatment of melasma, one of the pigmented dermatoses. To the best of our knowledge, based on a thorough search of literature, no clinical studies assessing fractional CO2 laser in treatment of freckles could be retrieved.
149 studies on the registry are indexed under Melanosis; 38 are open to participants now.
This study's enrollment of 20 is below the median of 40 across 139 interventional studies indexed under Melanosis.
Browse Melanosis studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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Exclusion Criteria:
Procedure: Fractional carbon dioxide laser
SmartXide fractional carbon dioxide laser (DEKA, Florence, Italy). Parameters adjusted for: Power 20 watts, spacing 200 µsec, dwell time 300 µm, stacks 1.
Also known as: Ablative fractional laser resurfacing
treatment success
reduction of freckles number and color density more than 50% in comparison to pre-treatment digital photos
Time frame: One month
Treatment safety
Absence of irreversible changes in color and texture of the facial skin, that can cause patient dissatisfaction
Time frame: three months
This study is completed, as verified in Apr 2014. You cannot join it, but the record below documents what was studied.
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Cairo University